While on their helicopter flight rotation, Mark and Susan find an injured family of four who they bring to the ER.

Encouraged by Carol, Mark finally asks Susan out. Benton tries to save a boy, despite the fact Doug thinks he's brain dead.

Carol has to fire two of the nurses. Meanwhile, Gant feels Benton is too hard on him.

Benton tries to find out if everything's OK with Carla's baby. Carter tries to get a man operated, despite the fact Anspaugh thinks he will die no matter what.

Benton takes a day off to help Carla. Carter finds out Edson falsified a chart.

Anspaugh is furious when Carter tells him he wants to quit surgery. Charlie is brought in with an overdose. Mark keeps struggling with his beating.

Mark treats an old lady who has been brutally raped. Carter's grandmother visits Carol's clinic. After he's touched by Benton, a blind man can see again!

Because of benzene that's been spread, the ER has to close. Weaver gets felled and Carter has to take the lead.

Carter finally works up enough nerve to ask Del Amico out. Jeanie tries to help Scotty decide whether to undergo an experimental treatment and Benton takes unexpected action during an operation with Morgenstern.

Ross and Hathaway's jobs are in jeopardy after their unauthorized treatment of a drug-addicted 7-month-old boy is discovered. Corday loses her sponsorship. Carter suspects Del Amico's boyfriend when drugs are stolen.

Dr. Corday commits a deadly error after being on-call for nearly 36 hours straight. Peter visits Dr. Kotlowitz and receives encouragement regarding a cochlear implant for Reese. Dr. Amanda Lee, a prospective new ER chief, visits. In the wake of a failed pregnancy attempt, Carol lashes out at a mother using abortion as a means of selective birth control. Carter and Lucy feud when Carter accidentally uses her palm computer and finds out what she thinks of him. Mark panics during a paramedic initation.

Carter and Lucy scramble across Chicago to find a dying girl's father who's a perfect match for her very rare blood type. Benton operates without transfusions to save the little girl's life.

Carter plays tour guide for Ruth Johnson, who was born in the hospital 100 years ago to the day, and her large family. Carol treats a boy who was hit by a car and tells a story of being chased, his friend being shot in the process. Peter observes Kotlowitz install a cochlear implant and decides to wait before scheduling an operation for Reese. Mark dines with Dr. Lee, new ER chief. Dr. Corday proposes radical changes in scheduling at an M&M conference, and later decides to break off her relationship with Benton.

When Anspaugh decides to retire as chief of staff and return to surgery, he appoints Romano as his replacement. Greene expresses reservations about the decision, but Weaver does not support Greene. Romano makes Weaver the new chief of emergency medicine.

After his mother's funeral, Dr. Greene comforts his father in San Diego. In Chicago, Romano surprises Corday by appointing her associate chief of surgery. Corday treats Elaine, Carter's lover, for breast cancer.

Kovac and Haleh take care of Hathaway's twins so the new mother can finally get some rest. The job transfer for Carla's husband does not get approved allowing Reese to stay in Chicago. Lucy endeavors to get a heart transplant for a young woman and goes to Romano's house begging him to perform the surgery.

Lucy's patient finally gets a heart transplant but does not survive. The transplanted heart will now go to another recipient. Greene interferes in a gay domestic situation. Corday tricked her patient who murdered several women and now he's being transferred to a county jail.

Carter and Lucy are discovered and the staff struggles to save them and go on with normal patient care.

Chen's patient refuses to reveal to his daughter that she might have inherited a terrible disease from him. Weaver defies Romano's authority and performs a procedure that gets her suspended. An available kidney causes friction between Corday and Kovac as they decide which one of their patients will get it.

Weaver returns to the emergency room after a self-imposed sabbatical of three weeks, wondering how her newfound lesbian identity will affect her workplace relationships. Having purposely allowed a mass murderer to die, Greene must keep the secret amidst the scrutiny of his superiors.

A new medical student, Michael Gallant, arrives in the ER. He's supposed to be working under Dr. Carter's supervision but his grandmother is unwell. Elizabeth Corday is convinced that other doctors are refusing to work with as a result of the mysterious deaths.

An accidental overdose brings Drs. Green and Corday's baby into the ER.

Greene confronts Corday when she orders Rachel out of their home; Abby tries to protect a battered neighbor who refuses to press charges against her husband.

Abby fears the worst when her brother Eric suddenly disappears. Carter and Chen treat a frightened Chinese immigrant nanny, Tong-Yi, whom they suspect was impregnated by her employer. Meanwhile, new surgical resident Paul Nathan, who is struggling to overcome a physical disability, tries to help in the emergency room—but his fellow doctors do not appreciate his advice to patients. Unable to quench his sexual appetites, Kovac also gets into trouble in his professional life, despite his admirable resolve to find an eye specialist to treat a young gunshot victim. Gallant and fellow medical student Erin Harkins engage in an escalating competition of medical knowledge. And Weaver gets some much-needed good news.

On Thanksgiving Day, a helicopter crash outside the ER leaves several injured, and kills Dr. Romano. Alex tries to bring Sam and Luka together.

While examining a young boy, Pratt finds a suspicious gash across his chest and calls Wendall for a consult. Kovac and Pratt examine a man who was shot when he confronted his boss with a gun. Jake tries to convince Abby to date him despite his being a student.