Shinichi Chiaki was almost giving up his dream of becoming a conductor, until he met Megumi Noda, also known as "Nodame". The pieces performed in the episode are Introduction and Rondo Capriccioso by Camille Saint-Saëns (brief), Piano Concerto No. 5 in E-flat major "Emperor" by Ludwig van Beethoven (brief), Piano Sonata No. 8, Op. 13 "Adagio Cantabile" by Ludwig van Beethoven (brief) and 2-Piano Sonata in D Major, K.448/375a by Wolfgang Amadeus Mozart.

A foreigner visits Chiaki's school and becomes friends with Nodame. Chiaki refuses to let him into his house because of his perverted behavior. It turns out the foreigner is Maestro Franz von Stresemann and is attending the school as head of the conducting department. Chiaki, interested in changing his major to conducting, gets rejected by the new professor who is apparently at odds with Chiaki's former "teacher", Vieira. The piece performed in the episode is Fantaisie Impromptu, Op. 66 by Frédéric Chopin (brief).

Chiaki takes part in his first competition as a conductor. But he ends up having to face strong contestants like Jean Donnadieu, one of Sebastiano Vieira's apprentices.

The Marlet Orchestra is short on staff, and Chiaki asks Nodame to take a part on it. However, Nodame's dreams of having her first performance along Chiaki are crushed when Rui is forced to assume her place due to a misunderstanding.

Chiaki's popularity ahead of the Martlet Orchestra keeps increasing while Nodame gets depressed as she feels the distance between them growing and she decides to enter in a competition by herself, even without her teacher Auclair's approval. Pieces featured: Bach's Concert No. 1 in D minor, Romeo and Juliet's Overture-Fantasy by Tchaikovsky, Études Op. 10 No. 8 and Op.10 No. 12 by Chopin

Thanks to Chiaki's encouragement, Rui decides to keep playing and a special concert featuring both is arranged. Stresseman is seriously depressed over the death of a friend of his and Chiaki, on the way to attend one of Nodame's recitals, have a surprising reunion with Sebastiano Vieira and he decides to accompany him instead. Pieces featured: Italian Concerto, BWV 971 by Bach, Op. 19 No. 1 "Sweet Remembrance" from Songs without Words by Felix Mendelssohn, Polonaise Fantasie by Frédéric Chopin, Légende No. 1: St François d'Assise by Franz Liszt

After Chiaki and Rui's concerto, Nodame and Chiaki spend the night together and she proposes to him in the following morning, just to be rejected by him. However, Chiaki starts to wonder about how serious she was at that time, and Stresseman pays a visit to her. Pieces featured: Piano Concerto in G major by Maurice Ravel and Third Movement of Piano Sonata No. 31 by Beethoven