Environmental toxins in a low-income housing unit trigger early menopause in one of its 25-year-old residents. A new mother spirals into depression and runs away from home. Dana meets Nick's mother.

The parents of conjoined twins refuse to have them surgically separated, even though that means they may both die. Lu suspects a leukemia patient may have attempted suicide by starting a fire. Peter is concerned about a patient with a severe rash on her arm and suspects it to be the some kind of virus. Dr. Jackson feels that Rittenhouse needs a good safety & emergency plan and he puts Lana in charge of it.

Lu's return to her college alma mater is marred by an outbreak of meningitis. At the clinic, Dana develops symptoms suggesting she is pregnant.