Emily talks about safe sex to some girls at a local high school; and she tries to forget about her feelings for Will.

Emily and Micah are frantic when they discover their patient needs a kidney transplant immediately, but they are baffled when she mysteriously refuses to accept the kidney from her new husband. Elsewhere, Emily assists Dr. Hamada (Brittany Ishibashi) and Dr. Bandari, with a risky surgery after they discover that one of the babies their patient is carrying for her sister suffers from a defective heart valve. Meanwhile, in an effort to keep Cassandra away from Will, Emily tries to land the job as Dr. Bandari’s research assistant. However, her competition is Cassandra, who is willing to play dirty in order to get what she wants.

Emily treats an infant and a deeply religious man whose faith is shaken following surgery. Meanwhile, Will breaks protocol with a risky diagnosis; and Tyra considers telling her father that she is a lesbian.

A beloved flower-delivery man collapses, but he is reluctant to get treatment. Meanwhile, Emily and Will are assigned to help a sick prisoner, but they find it difficult to remain professional and not let his crimes cloud their judgment.

A man gets admitted in a costume and claims to be King Paravel from the Elvish nation. The man later goes blind which leads Will to believe he is suffering from conversion disorder, a psychiatric problem. Emily refuses to jump to conclusion so quickly. Another patient is a woman diagnosed with cancer who later passes away due to an unexpected cardiac arrest. Her upset daughter sues Micah for medical malpractice. In an attempt to prove that she is not predictable, Emily agrees to let Tyra dress her up for a blind date arranged by Cassandra. Emily shows up to the date beautifully which later causes Will to act jealous. Micah realizes his true feelings for Kelly. Doctor Bendari realizes she has been putting career before life and attempts to change it.