Cicely's newest resident, Mike Monroe, is confined to live in a plastic bubble because of M.C.S. (Multiple Chemical Sensitivity), which makes him allergic to nearly everything manufactured in the twentieth century. After Maggie meets Mike she becomes interested in him. Ruth-Anne's son Matthew, the investment banker, comes to Cicely to try to get away from it all when he is fired from his job. Maurice's prospectus on making Cicely a place for sick people to move to and recover from their illnesses draws Matthew back into thinking about money.

The ever-quiet Bob returns to Cicely, with "The New Perception Players" and still hopes to win Marilyn's affection. Maurice receives a package from his son and it reminds him that he needs to adjust his will to cover his Korean offspring. Maggie tries to develop her relationship with Mike, by helping him with the revisions to Maurice's will. Ed is suffering from a creativity block and finds a ring with the initials F.F. engraved on the inside, and then he begins to have Fellini-like visions.

The Indians in Cicely celebrate Thanksgiving by throwing tomatoes at white people. Joel is Ed's first victim and he is angered because in his words he is "definitely not white." The town gets decorated with skulls and pumpkins as they also celebrate "The Day of the Dead." Joel also gets bad news in a letter telling him that he must serve another year on his contract. Mike's latest reactions to the environment are caused by something he can't trace so he thinks about moving to Greenland. Chris waxes nostalgic and decides that the something missing from his life is "the joint" when he finds a can of beans that he remembers from Thanksgiving.

Chris is taken into custody for an extradition trial to bring him back to West Virginia, where he currently has a parole violation. Chris knows he is guilty and really isn't interested in his defense. Mike comes up with an angle that he can prove to the judge that the Chris Stevens that skipped bail is different from the Chris Stevens standing before her.

Ed becomes gloomy about the future and begins to share Mike's visions about the future. Maggie digs up some artifacts from an ancient female in her front yard and Maurice wants to turn it into a major excavation. A young boy who runs away from a survival camp gets a job at "The Brick" to cover his room and board; he also falls madly in love with Shelly. Maggie and the rest of the women band together against the men who have dominated the dig in her front yard.

One-Who-Waits returns and has positive information on the location of Ed's father and takes Ed to the construction site where he works. Ed gets a job and tries to come up with a way to tell the foreman that he is his father. Mike asks Maggie to fly to a mountain range where he thinks he will be able to identify the chemicals that were part of a container spill. A blind man comes into "The Brick" and offers to tune and rebuild the piano but begins to get on Holling's nerves. Maggie tries to hold off Mike's advances by telling him about her "curse."

Maggie forgets about having sex with Joel. Holling and Ruth-Anne go out to find a Siberian Tit, a bird rarely seen in Alaska. Ed's uncle arranges a marriage for Ed; however the bride already has a boyfriend.

Joel goes on strike when the state of Alaska will not allow him time off for a Caribbean vacation he was planning. Chris has trouble seeking inspiration for his new sculpture. A vagrant's presence on Main St. outrages Maurice, when he learns the man is an ex-marine he tries to become his benefactor. Maggie debates about having sex with Mike. Holling spends his time in hibernation. The town of Cicely strikes back against Joel.

A totem pole carved in tribute to the Raven clan reopens a bitter rift between them and the Bear clan. Shelly gets medical advice telling her that getting married may help her to get rid of the strange hallucinations with dancers that she's been having. Joel confronts Maggie about their "whatever" and her relationship with Mike; together they decide they're "mutually desirous incompatibles."

Maggie is excited when she thinks she has "cured" her latest beau, as opposed to killing him; however she is crushed when he tells her that he leaving to work for Greenpeace in Murmansk. Holling is disgusted by Shelly's redecorating of their bed & bathroom. Maurice moves his childhood home to Cicely and it stirs up memories of his brother.