Jake and Jo see the Carters arrive at the cabin with Emily and the baby. While Jake is calling the police, Jo disobeys his wishes and confronts the Carters. Mr. Carter shoots her in the back. Mrs. Carter sneaks into Jo's hospital room in the middle of the night, and threatens to kill Austin if she does not receive custody. The judge nullifies the previous custody arrangement, and agrees with Jo's suggestion that the baby be given up for adoption. Amanda is fired after testing positive for illegal drug use. Amanda and Matt discover that Peter prescribed pills for Amanda that contained the active ingredient in marijuana. Although Amanda has no proof, Peter believes her bluff. He knocks her out and plans to kill her on the operating table. Michael pulls the scalpel away and breaks Peter's nose. Michael and Amanda interrupt a D&D meeting where Caitlin is to be appointed president, and discredit her. Alison stops Terry from drinking after he loses a playoff game. He expresses his gratitude

Rikki commits acts of vandalism against Jo, Jane and Jake, who believe that Syd is responsible for the crimes. The isolated Sydney is forced to turn to Martin's cult for comfort. The visiting Meredith admits that she has never slept with a man because of the trauma of the childhood abuse. She tries to seduce Billy. The new chief-of-staff institutes mandatory psychological testing for the staff. Kimberly's test proves that she is extremely disturbed and highly dangerous. She has some men on the street assault test coordinator Matt, then changes her results while he is out of commission. John Rawlings, the police detective investigating the case, befriends Matt. Billy is concerned by Amanda's deteriorating health, and asks Michael to check her out. Amanda is horrified when tests reveal that she has Hodgkin's Disease.

Samantha takes back Jeff after learning that his knee injury has ended his career. Amanda catches Billy and Jennifer making out at the jazz club, and drops hints about Sam's affair. Billy shows up at a little league game where Jeff is coaching, and sees Sam kiss him. He punches Jeff, and Sam is knocked unconscious during the scuffle. She lets Billy take her home from the hospital, but he refuses to talk to her. Taylor tells Kyle that he is the father of her baby. Amanda learns about the pregnancy, and Michael claims that Kyle is the father. Amanda goads Kyle into signing divorce papers, as she plans to get a quickie divorce in the Dominican Republic. Rory asks Amanda to marry him. Megan and Brett get engaged. Dr. Larner attacks Megan, but Brett comes to the rescue. Larner's wife tells Megan that her husband is influential, and that Brett is being asked to choose between the job and Megan. Megan tries to leave Philadelphia, but Brett stops her and says he rejected the job. Lexi becomes