A software glitch causes Cameron to forget who she is. She goes missing from the Connors and is taken in by a street kid named Jody. Cameron and Jody end up at a halfway house where Cameron meets with a social worker who uncovers some of Cameron’s distant memories. Meanwhile, Catherine Weaver meets with Agent Ellison to discuss his future at Zeira Corp, and Ellison does some digging into Weaver’s past.

While Sarah, John and Cameron track another name from their list, they accidentally cross paths with T-1001. Meanwhile, a woman who Derek once knew in the past surprises him by appearing in the present.

The Connors visit a town connected to the destroyed factory; Weaver sends a man into town in search of a survivor.

As the Connors prepare to move, they find out that Riley is dead, and Sarah begins to doubt Cameron's motives. Jesse flashes back to a submarine mission in the future, and John Henry plays hide and seek with Catherine Weaver's daughter.

Sarah and John hit the road without Cameron and Derek to stay with Charley Dixon, where she reveals to Charley that her cancer may have emerged. Meanwhile, a computer worm infects John Henry.

When John attempts to rescue Skynet’s latest target he finds himself closing in on Weaver, but at what cost? Game plans change, causing Sarah and Ellison to reunite. Meanwhile, Weaver learns Ellison’s secrets.