Chef Tom Colicchio learns the hardships his family endured in Northern Italy; chef Ming Tsai traces his roots back 2,000 years; chef Aarón Sánchez learns his Mexican roots include Spaniards, Africans and Native Americans.

Secrets encoded in their genomes challenge these guests’ ideas about their families’ histories and their identities today. This episode features Jessica Alba, Anderson Cooper, Valerie Jarrett, Governor Deval Patrick and more.