October 14, 1964: Since mainstreaming the mentally disabled is not yet a popular concept, Sam must help Jimmy LaMotta, the "slow" young man he's leaped into, get a job and gain his co-workers' acceptance, to prevent his brother from returning Jimmy to the institution.

August 19, 1963: Sam finds himself in one holy mess as a priest in Philadelphia, trying to help an alcoholic priest deal with a killer and the death of a young parishioner.

May 9, 1974: Leaping into magician Harry Spontini, Sam has to prevent his estranged wife from taking their daughter away from him as she files for divorce, so she can marry her sleazy divorce attorney.

September 1, 1958: As "Bones," a member of a motorcycle gang, Sam is an uneasy rider who has to prevent a Jack Kerouac-inspired young woman from meeting her death on the road.

November 15, 1955: Billie Jean Crockett is a pregnant teenager who will make the second biggest mistake of her life - giving her baby up for adoption - unless Sam, as Billie Jean, can convince someone to help her raise her child... before he goes into labor himself

November 10, 1985: Joey Dinardo is a lounge lizard on the run from mob hitmen. When Sam leaps in, his ex-girlfriend, and former musical partner have found him, and now both are on a run for their lives from a killer who seems to know their every move.

October 26, 1962: Sam finds himself the brother of a fallout shelter salesman during the Cuban Missile Crisis, where he must defuse a potentially explosive situation as panic sets in on the night of John F. Kennedy's speech to the nation.

June 25, 1957: Sam leaps into Al Calavicci to prevent the death of his married lover. But when Sam accidentally alters history, and finds out too late about her untimely demise, it could mean the gas chamber for Al and disturbingly a whole new situation at Project Quantum Leap.

October 5, 1957 - November 22, 1963: As a result of leaping again before he had a chance to complete his original mission, Sam finds himself leaping back and forth through the life of Lee Harvey Oswald. Following the sole assassin theory, Sam and Al attempt to prevent Oswald's attack on John F. Kennedy. But, with each leap giving Oswald more control over Sam's body, history seems doomed to repeat itself.

October 5, 1957 - November 22, 1963: As a result of leaping again before he had a chance to complete his original mission, Sam finds himself leaping back and forth through the life of Lee Harvey Oswald. Following the sole assassin theory, Sam and Al attempt to prevent Oswald's attack on John F. Kennedy. But, with each leap giving Oswald more control over Sam's body, history seems doomed to repeat itself.

August 8, 1955: A pair of unsolved murders marks just the tip of the iceberg when Sam leaps into a sheriff in a small Louisiana town. Rumors of a history of family insanity, the suspicions surrounding his daughter Abigail's involvement in the murders, and ghostly visions of his institutionalized wife just make matters worse.

June 14, 1966: Finding himself back in the same small Louisiana town, in the arms of Abigail, now twenty-one, Sam must prevent an angry crowd of townspeople from lynching his fiancée, following the disappearance of a young boy whom she had been babysitting.

July 28, 1978: Sam is an aging lawyer, recruited by Abigail, now thirty-three, to defend her when she is put on trial for the murder of Leta Aider, the woman whose daughter Abigail was accused of killing almost twenty-five years earlier.

July 3, 1954: Sam swivels his hips into Elvis Presley, mere days before he is discovered. Along with making sure that Elvis does become the King, Sam must help Sue Anne, a local songbird, from being trapped in a not-so-gilded cage of marriage.

August 8, 1953: Sam lands in a not-so-ordinary bar in a coal-mining town, where strange things are happening and familiar people don't know him. With the help of another Al, he still has something to set right ... or is there more than one thing he needs to change?