When Zoe reads about her fellow classmates’ accomplishments in her Alumni magazine, she is upset that they list her as “retired” and invites the reporter to BlueBell for an interview. However, Zoe has a hard time convincing the reporter that she actually has a thriving medical practice in BlueBell – that is, until she comes across a rare and potentially serious disease. Trying to be considerate of Lemon’s feelings, George informs her that he is going out on a date, making her feel that she too needs to find a date. Meanwhile, Lemon and Lavon both find themselves in competition with their nemesis Ruby.

Wade struggles with feeling like he’s a placeholder in Zoe’s life, so he decides that they should go on a date. Despite Zoe’s apprehensions, she decides to bid on Wade’s basket at the upcoming charity picnic auction, but is surprised that she is not the only one interested. Lemon mistakenly wins Lavon’s basket and decides to keep her true feelings for him to herself and instead offers some advice about his relationship with Ruby. Meanwhile, George is interested in dating Tansy and creates a basket that he hopes she will bid on.

When Zoe is alerted by the Health Department about a flu epidemic heading towards BlueBell, she is forced to put the town on lockdown. Because of the quarantine, Wade is forced to stay at his ex-girlfriends house causing Zoe to become jealous. Lemon’s plan for the perfect night with Walt goes awry when she begins to feel under the weather. Meanwhile, George finds himself roped into directing Lavon’s tourism commercial about BlueBell’s small-town charm, but it seems Lavon, is more preoccupied with his co-star than his commercial.

Wade is excited to compete in the Battle of The Bands competition so he can use the prize money to open up his own bar, but Zoe’s suggestion that George play in the band ultimately backfires. Lemon finds herself alone for the weekend until she talks Magnolia (Claudia Lee) into some sisterly bonding. Meanwhile, Lavon, who has seemingly given up on love, agrees to help Tom (Ross Philips) with his relationship, which in turn opens his eyes to his own future.