Queen, the Lead Performer, blazes away at samurai on the Performance Floor with the special version of the Plague Rounds, which turns them into hideous ogres that corner Zoro and Drake. Meanwhile, Luffy and Sanji, who are on their way to the rooftop, run into another Headliner with a special ability.

King orders his subordinates to go after Momonosuke. Shinobu tries to protect him, but they are cornered by one of the strong Lead Performers from the Animal Kingdom Pirates. Meanwhile, seeing people suffering from Queen’s Plague Rounds, Chopper is determined to save everyone.

Yamato fights Sasaki and the Animal Kingdom Pirates Armored Division to protect Momonosuke. Meanwhile, Zoro tries to get rid of the Gifters who have turned into Ice Oni, but Queen starts a horrible game which involves the antibody for the virus.

Ulti and Page One of the Tobi Roppo chase Nami and Usopp, after being infuriated by their attack as well as Luffy’s declaration of becoming the King of the Pirates. Cornered, Nami gives in and Ulti pushes her to say the unthinkable.

Carrot and Wanda step in to help Marco, who is cornered by Big Mom and Perospero. In the meantime, Yamato fights a fierce battle against the Animal Kingdom Pirates Armored Division led by Sasaki, while protecting Shinobu and Momonosuke.

Zoro and Drake continue to chase Apoo to get the antibody against Ice Oni, while Chopper is trying to figure out how to fight the virus. In the castle, Luffy, Jimbei, and Sanji are climbing up the stairs to reach the rooftop where the Akazaya members’ tough battle against Kaido rages on.

Sanji hears a woman’s scream for help and dashes into the room the scream can be heard from. However, it’s a trap set up by Black Maria of the Tobi Roppo. Meanwhile, Luffy and Jimbei who are trying to reach the rooftop get help from the unexpected.

While Kaido begins the New Onigashima Project, Marco appears in front of Chopper and the others, who are struggling with Ice Oni. The members of the Tobi Roppo continue to give the Straw Hats a hard time while their former member helps Zoro.

Yamato tells Momonosuke and Shinobu that he once confronted a man, who came to Onigashima looking to get Kaido’s head. His name was Ace. The two of them engaged in a fierce battle that eventually turned into an important friendship.

The formidable Lead Performers of the Animal Kingdom Pirates stand in Zoro’s way as he tries to get to the rooftop. Marco sees his late comrade in Zoro’s determination and tries to pave the way for him.

Yamato tells Momonosuke and Shinobu about how Ace gave him hope for the future. Meanwhile, Luffy and the other allied pirates from the Worst Generation make it to the rooftop to finally face off against Kaido and Big Mom.

Luffy’s strong attack reminds Kaido of all the strong ones he’s ever met. On the other hand, Luffy, Law, and Kid keep quarreling amongst themselves. Meanwhile, Sanji is caught and interrogated by Black Maria in what he calls “heaven.”

Luffy, Law, Kid, Zoro, and Killer keep landing hard blows against Kaido in tandem despite the arguing. However, when Big Mom steps in and unleashes powerful lightning strikes, the tide turns for all except one of the rookies.

Luffy pummels Kaido with his well-trained Kong Gatling and delivers a final blow using all his strength. Big Mom tries to fight back, but Law gets in her way and Kid and Killer also try to finish Kaido off.

After watching the Straw Hats’ departure to Onigashima, Tama wondered if there was anything she could do to help the Straw Hats and the samurai. Now that she’s here on Onigashima, it’s time to execute her powerful plan – Operation Kibi Dango!

Sanji is captured and tortured by the merciless Black Maria. She names the terms of his release: to turn over one of his crewmates. He hesitates but has no other option. After much distress, he makes a move that surprises everyone.

Robin bursts in to rescue Sanji along with Brook, and faces Black Maria, who is trying to keep Sanji as her pet. Meanwhile, Yamato, Momonosuke, and Shinobu are spotted hiding by the enemy, and they find themselves on the run again.

Chopper works hard to make the cure for Ice Oni, even though he is turning into one himself. Meanwhile, the infected Boss Hyogoro the Flower regains his youth and fights fiercely to protect Chopper and the others.

Seeing everyone turning into Ice Oni, there is nothing that the samurai warriors can do other than grieve. However, it wasn’t just them who were devastated by Queen’s raging virus. When their desperation and frustration peak, they hear a hopeful voice.

That unparalleled laugh! The Akazaya regain hope upon witnessing Oden's return. They failed in their attempt to take down Kaido, but after twenty years, they team up with Oden again to finish the job!

The Akazaya members run to save Momonosuke, but an unexpected contender stands in their way. Queen gets infuriated after Chopper ruined his plot and goes after him. Meanwhile, on the rooftop, Kaido and Big Mom unleashes a combination attack on Luffy and the others.

The returned Orochi clashes the Akazaya members who are trying to save Momonosuke. Meanwhile, Luffy and the others are all covered in bruises, but they unite their strength and launch an attack.

Even after Big Mom was pushed off of the island, Zoro and the others keep fighting the exhausting battle against Kaido. When Kaido tries to beat up the unconscious Luffy, Zoro launches an all-out attack at the risk of his life.

Luffy remembers how he was advised by his friends, how he was saved by his comrades, and the frustrations of being defeated. As Kaido mocks him to his face, the Color of the Supreme King Haki gushes out and they clash again.

A young Luffy who has been dreaming about getting out of Windmill Village one day to accomplish something great meets a young girl named Uta who came along with Shanks and the Red-Hair Pirates calling herself the musician of the pirate group.

Luffy and Uta run across Windmill Village, compete with each other, and share their dreams with each other. They also pledge to build a new genesis for everyone to live happily. However, one day, the unexpected happens.

Luffy and Kaido who have both infused themselves with the Color of the Supreme King clash! Meanwhile, Nami, Usopp, and Tama are running from Page One to get to the Performance Floor, but they bump into another tough enemy, Big Mom.

Kin’emon and the Akazaya members are rushing to help Momonosuke and everyone else while Yamato leaves Momonosuke and Shinobu in a hide-out to lure away their enemies. At the same time, Ulti tries to avenge her brother against Big Mom.

Sanji is forced to run with Zoro on his shoulder. Meanwhile, Nami bravely stands up against Ulti and Big Mom. On the rooftop, the intense battle between Luffy and Kaido finally comes to an end.

Luffy is pushed off the rooftop by Kaido. Meanwhile, Zeus intervenes in a fight between Big Mom and Nami’s group and stands up for the one who he wants to save. On the Performance Floor, Chopper is in a fierce battle against Queen.

While the Straw Hats and their allies are all having a hard time, they are shocked by the news that Luffy lost to Kaido. At the same time, Kanjuro closes in on Momonosuke to destroy the Kozuki lineage.

Like all the other samurai, Chopper is discouraged by the news of Luffy’s loss and Queen doesn’t miss the chance to finish him off! Meanwhile, Kin’emon fights for his life to save Momonosuke and that motivates Momonosuke to rise up!

Momonosuke and Shinobu face Kaido while Kid and Law challenge Big Mom. Meanwhile, Nami, heading towards the stage on the Performance Floor along with Usopp and Tama, hears a strange voice.

Nami strikes a thunder blast to clear the way to the stage on the Performance Floor. However, the elite corps of the Gifters shows up to crush their inferior opponents. Upset but unbroken, Otama stands up to give a command!

Hearing Otama’s command, the Gifters side with the samurai and upset the Tobi Roppo and others! Chopper starts to take care of Zoro while suffering from the side effect of the enhanced Rumble Ball. Meanwhile, Jimbei gets stunned by Who’s-Who’s story.

Who’s-Who expresses fierce resentment toward Luffy and Jimbei fights back out of his loyalty to Luffy. As Who’s-Who asks Jimbei a question, he tramples on the dignity of the Fish-Men and that sparks Jimbei’s outrage.

To cut ties with Kaido, Yamato unleashes his true power. Meanwhile, Queen repeatedly attacks Sanji with his power as a cyborg, and Sasaki in his Man-Beast Form launches tricky attacks on Franky and drives him into a corner.

Kaido tries to convince Yamato to become the Shogun of the Land of Wano and rule the country with the special power he obtained by accident. Meanwhile, Saul, Professor Clover, and Robin’s mother Olvia suddenly appear in front of her.

In the dense mist, Brook is surprised to see his old friends, the Rumbar Pirates and Laboon. They reminisce about the old days and play music together, however, they suddenly attack Brook.

Black Maria torments Robin both physically and spiritually. As she burns in hellfire, Robin remembers the people who gave her a hard time and the people who supported her, and she as Demon Child shows what she is really capable of.

Killer is shocked to find out who Hawkins’ straw doll he slashed represents. Meanwhile, Sanji who is in a hard battle against Queen and King sees enemy brutes going after the injured Zoro, and no one else is there to save him.

Zoro gets back on his feet and along with Sanji, confronts King and Queen, the Lead Performers of the Animal Kingdom Pirates. Watching Zoro fight, Hyogoro and Kawamatsu remember someone from way back.

Dogstorm confronts his sworn enemy who destroyed his country. Meanwhile, Cat Viper faces Perospero who is responsible for Pedro’s death. At Tokage Port, Momonosuke roars with his determined eyes.

The battle between Kaidou and Yamato gets intense. Backed into a corner, Yamato remembers three great swordsmen who he met when he was a child. Their stunning choice for the future of the Land of Wano encourages Yamato.

Luffy amps up the reluctant Momonosuke, who is afraid of heights, in his giant pink dragon form, to fly and take him to Onigashima in the sky. Meanwhile, Yamato, in a hard battle against Kaido, vows to survive until Luffy returns.

Momonosuke faces Kaido once again trembling in fear. However, with Luffy’s encouragement, he bravely steps up and shows his dragon fangs remembering what he had to go through because of Kaido.

Yamato helps Momonosuke conquer his fear of flying and the two take on the most important task of saving Onigashima. Meanwhile, Luffy and Kaidou clash which parts the heavens. The clear skies help Inuarashi and Nekomamushi finally defeat their foes.

Realizing Onigashima’s impending threat, imperiling everyone’s life, Yamato and Momonosuke launch a secret operation. Meanwhile, Sanji and Zoro are both in a deadly battle against Queen and King.

Queen’s unforeseen move stuns everyone on the Performance Floor. And then, he goes on to utilize another special technique which can break every bone in Sanji’s body. On the verge of a crisis, Sanji feels something strange again.

Killer tries to figure out how to fight against Hawkins whose power enables him to transfer damage against him to Kid. Kid is dying not knowing where his damage is coming from. Killer takes a chance with Kid’s life on the line.

Sanji still wonders what is happening to his body as he receives attacks. Meanwhile, the dying Kin’emon hears an unexpected voice calling for the also dying Kanjuro. Through the Smail, the voice of Orochi tries to stir up Kanjuro to make him perform one last time.

Law and Kid are having a tough battle against a formidable Emperor of the Sea, Big Mom. However, when they decide to work collaboratively and use their awakened Devil Fruit powers, they see the possibility of taking down the old generation.

Sanji is tormented by the idea of becoming a cruel Germa warrior like his siblings and torn between being strong or being humane as he is now. When he makes up his mind, he asks Zoro the ultimate favor.

The chaos within the floating island of Onigashima rages on to seemingly no end. Kazenbo, Kajuro's creation, is wreaking havoc all throughout the Skull Dome in the name of vengence for the Kurozami. The rampage causes panic among Beasts Pirates and samurai, alike. As Orochi watches on, he hears a sound that reminds him of his past love.

Zoro is facing a hard fight against King who seems invincible. Even one of Zoro’s deadliest attacks doesn’t leave a scratch on him. On top of that, one of Zoro’s swords goes out of control and gets in his way.

Zoro still can’t gain control of Enma which keeps extracting his Haki. Backed into a corner by the formidable King, Zoro remembers the encounter with an old man in his hometown when he was a child.

Queen’s formidable attacks remind Sanji of his family. Annoyed by Queen’s provocations, Sanji remembers a young woman mysteriously getting hurt in front of him and realizes what happened at that time, which lights a fire within him.

Zoro tries to figure out a way to damage King. Meanwhile, King remembers when he first met his captain Kaido and declares that his captain is the one to become the King of the Pirates, which leads Zoro to set his swords alight with hellfire.

Usopp finds Kin’emon’s upper body and the heavily wounded Kiku. However, they are surrounded by the Gifters and can’t find a way out. Seeing the samurai giving up hope, Usopp remembers his determination.

In the Flower Capital, the Fire Festival is about to end. On Onigashima, the battle between Luffy and Kaido is getting even more intense. However, Kaido who is excited about having a strong opponent starts drinking too much.

With the ongoing battles in various parts of Onigashima, everyone is reaching their limits. In the face of Big Mom, Law and Kid are exhausted and deeply wounded. Mocking them, Big Mom tries to head for the rooftop.

Big Mom’s strong life force discourages Law and Kid. Law tells Kid that he only has enough energy for one last strike. However, a monster Big Mom summons puts the two in even more of a bind.

Kid’s all-out deadly attack and Law’s tactical action leave Big Mom in the lurch. Then she remembers what Roger said in the past and wonders if the treasure he mentioned is out there after all.

Kaido mourns Big Mom’s defeat and remembers the day he met her for the first time. Meanwhile, backed into a corner, Orochi sees the true nature of Komurasaki, the woman he loves, and trembles with fear.

On orders from the Five Elders, the CP-0 agent Guernica tries to get to Luffy, but Drake stands in his way. Meanwhile, Luffy who only has very little energy left uses his last Gear Four to emancipate the people of the Land of Wano from Kaido.

The battle between Luffy and Kaido comes to an unexpected end. Kaido comes down and tells everyone that Luffy has been defeated and the Land of Wano is finished. Momonosuke and Yamato argue over whether they should still continue fighting.

As Luffy's heart pounds in a funny way, the Five Elders reveal the secret behind the Gum-Gum Fruit. Meanwhile, Orochi tries to convince Komurasaki to escape with him, but when he sees Kanjuro, he makes a malicious decision.

Bouncing on the ground and becoming a giant, Luffy enjoys his new, bizarre power while Kaido is bewildered and can’t make sense of it. Meanwhile, Kid, Law, and Luffy’s other allies continue the fight down below against flames and enemies alike, waiting for Luffy to emerge victorious.

As Luffy and Kaidou continue their battle, Raizo and Jinbe utilize their plan to put out the fire that has spread throughout Onigashima. Meanwhile, Yamato warns Momonosuke of the danger Onigashima will face if he does not act soon to create new flame clouds to keep it from crashing into the Flower Capital.