A village is tormented by a Yoma, which is a demon that has disguised itself as a human it has eaten. As a last resort the Chief of the village has ask for the help from a Claymore, who are feared as they are half human, half Yoma. Raki is a young boy who has found an interest in the Claymore and he begins to follow her about until later when he discovers who the Yoma is.

It doesn't take much effort for Claire to quickly complete her job and so Claire and Raki are off while she waits for another job. A strange man from the organization comes to give Claire a new set of clothes but not only that, he also gives Claire a "Black Card". What does this Black Card mean to Claire? Raki later has an encounter with the same man from the organization, who explains to him exactly what Claymores are (half human, half Yoma).

Three Claymores arrive in the town of Toriro to only find Claire, who has already taken care of the Yomas. It is revealed that what Claire defeated in the Holy City was not a Voracious Eater but a regular Yoma; because Voracious Eater is a public term for what the organization labels an "Awakened One". Claire has been added to the expedition team to hunt an Awakened One, as a chance to measure the limits of her skills. How will Claire ranked no. 47, fair against such a powerful being after a shocking turn of events?

By working together, Miria and Claire were able to defeat the Male Awakened One, which surprised the handler observing the battle but the team are left with injuries all over the place. In the meantime while they recover from their injuries, they begin talking about their past and it seems like they all have something in common that led to them being teamed up together. It is revealed that they have all experienced the Awakening process in the past.

Claire has separated from Raki in order to save him from the merciless Ophelia, who is currently pursuing Claire. It doesn't take long for Ophelia to catch up with Claire, where she is forced to fight for her life. With Claire putting up a good fight, Ophelia gets excited and decides to reveal the secret behind the name she gave herself "Ophelia of the Ripples". Claire is now in a dire situation, yet there was no chance of winning to begin with, when suddenly a familiar face appears from the shadows.

The Organization is getting uneasy of no. 47 Claire, after receiving no contact from her for three months. Following recent events, they end up taking drastic measures by sending out a Claymore on the mission to find Claire and it's made top priority. Meanwhile Claire is searching for Raki but while doing this a Claymore expedition team pass through the town, to hunt down an Awakened One; in the mountains nonetheless something seems odd about the situation.

In the Northern country Raki is with two surprisingly helpful people however he is unaware that these two are the two most powerful Awakened Ones in the area; "Priscilla" and "Person of the Abyss, Isley". Meanwhile after having just survived the first attack, the teams of Claymores are recovering and replenishing their supplies along with some interesting developments.

In the middle of an active volcano, Claire and Priscilla are finally going to face-off and even in her partially Awakened form Claire is still not any closer to being a match for former no. 2 Priscilla. For whose sake is Claire willing to risk her life for? Just when Priscilla was about to finish things Miria, Helen and Deneve arrive just in the nick of time, although what can they do against this formidable foe, who hasn't even shown her latent power.

The battle between the two awesome powers Claire and Priscilla reaches its climax as Claire somehow manages to gather the strength and determination to go on. Raki and Jeane have also arrived to witness the bloodbath that is about to begin, yet what will be the overall outcome of this battle?