It's the big wedding day for James and Ophelia, but before the knot can be tied the groom goes AWOL.

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It's a new school year and the gang's not all here. Dean Loward is determined to rid the campus of Omega House and his plan includes demolition. James attempts an intervention with the demo man by reviewing the events of the previous school year.

One returnee is Karen who protests the destruction of he campus home. She returns along with her soon to be divorced father and stepmother. Daddy suggests that Karen and her friends live this year in his vacation home. Karen agrees and thus, Omega house moves to a luxury dwelling where James continues reliving memories of the previous year.

Dean Loward decides to let James graduate in order to be rid of him. Zach, Karen and Larry rent a dilapidated Frat House with incoming freshmen Victoria, Maxwell and Olga, and throw a farewell party for James. But will James really be able to leave college life and his merry band of friends?

On the morning after the party, Olga, Victoria and Maxwell wake to confront their actions of the night before. James discovers that his ex-wife, Layla, has enrolled as a student, while Larry gets paired up with his former girlfriend, Ciara, in film class. Dean Loward remains determined to get rid of James, and puts obstacles in the way of his success.