Throttle, Modo and Vinnie...The Biker Mice from Mars...escape their planet as it it devastated by the fish faced plutarkians. Crashlanding in Chicago, the renegade rodents soon discover the Plutarkians next target: EARTH. Led by his supreme chessiness, Lawrence Limburger, and his devilish cohorts, Greasepit and the fiendish Dr. Karbunkle, the Plutarkians are already undermining the Windy City. It's tail whippin' time 'cause the baddest motorcycle mammajammers in the universe are riding to the rescue.

Limburger frames the mayor's kidnapping on the Biker Mice, so he can take over the city.

When Modo is covered in toxic substances, Limburger escapes with his bike. Modo does not want to rest while Charley and the guys rescue his bike.

When Limburger disappears mysteriously, his unintentional replacements turn out to be increasingly more powerful and evil.

After losing his funding, Limburger has a wonderfully devious plan to get back in the High Chairman's good graces, and this leads the mice and Charley in a race to save a national monument.

When the Biker Mice finally capture Limburger, they must return with him to Mars to face trial. They discover that they are also thrown in prison for treason. The Mice have to escape and save Charley from Greasepit and Karbunkle while claiming that they have not done anything wrong.

The Mice must now face Limburger's latest machine from annihilating Mars. The machine attracts asteroids to the planet, to bring complete destruction.

They still have to roost Napoleon Brie from Chicago where he's taken over in Limburger and the mice's absence.

Limburger decides to lure the Biker Mice into a trap that will put them against several villains. This would make Limburger gain access to Vinnie's Motocross title as the prize.

A female bounty hunter is present in the Windy City, ready to defeat some evil.

When, Limburger takes over as warden for a prison, Charley and the Mice find out a way to stop him, by trying to get into jail.

When intergalactic game hunters catch Modo's nephew Rimfire, he manages to escape in their ship and finds himself on Earth.

The Mice and Charley must travel to Kansas to stop Limburger from stealing all the grain from the nation's breadbasket.

The Pit Boss is back with a new friend, framed for a crime he did not do, while the Pit Boss captures Charley.

Limburgers decide to take all the water of Lake Michigan to pollute and send to Plutark as designer water.

Karbunkle has a wonderful machine that can remove comic book characters from their pages, and Limburger decides that the best way to defeat the mice is with evil versions of themselves.

Limburger disrupts Chicago's garbage service in order to bomb Chicago with stink bombs. He brings the scum of the universe back as his villains of choice for the task.

The guys manage to mess up the launch of Limburger's satellite, but must race Limburger to the North Pole to retrieve it and destroy it before Limburger can find it and get it in orbit.

When Limburger opens a new casino island, the Biker Mice needs to travel there to beat him at his own game when he uses less than honest means to win the land from many Chicago citizens.

The Mice have to deal with a meeting in Chicago of several of the largest Plutarkian bosses on earth and stop a Plutarkian invasion.

Limburger uses Karbunkle's newest machine to steal the land from fictional places in Shakespeare's plays. This resulted in the destruction of the plays, and they ceased to exist. So, the Biker Mice must enter the well-known stories to stop him, but first Charley must convince them that Shakespeare is worth saving.

Asphalt Jack returns to Chicago to visit Charley and friends with his fiancé, but the visit turns sour when Jack and his new cyber bike are captured and the guys must rescue him while Limburger and Brie deal with a quadruple, triple, double agent who has deals with more then just the two Plutarkians.

Limburger is ready to use a new device, a Tug Transformer, to bring Earth into orbit of Plutark.

Limburger is about to make Earth one of the newest moons of Plutark as the Biker Mice reveal to Charley about the time they dealt with the same problem back on Mars.

The Biker Mice retell the stories of how Modo got his arm, Vinnie his mask, Throttle his eyes, and a betrayal that resulted in the disappearance of a friend.