Megan is surprised to discover she has a connection to a woman found dead in a hotel room; Megan starts taking an interest in what is going on around her.

A magazine editor is found dead in her mansion; Megan confronts a suspect while at a social event with her mother; Ethan surprises Kate with his positive attitude.

Megan and the team investigate when a Philadelphia homicide detective is killed in a hit-and-run; Megan turns to her mother (Joanna Cassidy) for help.

The investigation into a fatal car crash reveals the seedy underbelly of a perfect-looking neighborhood.

A new investigation is opened up after a man assumed to be dead disappears off Ethan's exam table. When another body is found, it's the DNA evidence that leads to an eye-opening discovery.

After Peter rescues a woman from a house fire, Megan discovers another person in the house who died. Peter takes the discovery personally since he had no idea anyone else was in the house. A veteran arson investigator challenges Megan at each step in her investigation. When Megan complains to Kate the response she gets only intensifies the tension between the two women.

A champion equestrian is killed and potential drug use is suspected, but when Megan's daughter, who also rides, overhears details of the case, she leads the team to a clue and possibly the murderer.

When a popular 17-year-old high school student is found dead after a rave, the team must decipher various unknown drugs in his system and multiple bruises to figure out the cause of death. Meanwhile, Meghan is finally starting to date again after the divorce, but her ex-husband springs some shocking news on her and her daughter, causing tension at home.

An undercover cop is discovered murdered at a truck stop.

When the owner of a family owned and operated Italian restaurant turns up dead in the freezer, Dr. Hunt and the team take a closer look into family matters. Meanwhile, Peter must face his own haunted past.

After a car accident reveals a dead body in the trunk, the team is led to another body, giving the team two cases to solve; Megan is reconnected with an old acquaintance; Kate's job is threatened.

When two young girls are in a tragic car accident, one is left in critical condition and the other is found dead at the scene. As Megan and her team investigate the case, however, they realize there has been an awful mistake. Not only was the wrong girl pronounced dead, but the car accident may not have been the actual cause of death.

The team needs to quickly figure out how to treat the virus when more and more people are becoming ill and dying.