A female jogger is found dead in Schuylkill River and Megan teams up with medical investigator Peter Dunlop to investigate her whereabouts before her murder. Meanwhile, Megan spends the day trying to solve a personal problem concerning her daughter's birthday.

When a young, interracial couple is found shot and killed inside their car in Fairmont Park, Dr. Megan Hunt promises the grieving parents that their daughter’s killer will be found. Detectives Bud Morris and Samantha Baker are ready to chalk the case up to a murder-suicide, but Megan and her team find evidence on the bodies that sends the case in an entirely different and shocking direction. Meanwhile, Peter advises Megan not to push too hard when it comes to reconnecting with her daughter, Lacey.

When a young nanny is run down by a car and killed, the 5-year-old child she was watching is kidnapped; an interrogation goes awry.

When a popular 17-year-old high school student is found dead after a rave, the team must decipher various unknown drugs in his system and multiple bruises to figure out the cause of death. Meanwhile, Meghan is finally starting to date again after the divorce, but her ex-husband springs some shocking news on her and her daughter, causing tension at home.