After successfully breaking out of Itachi's Tsukiyomi, Sasuke gains the upper hand on his weakened brother. With no other alternative, Itachi activates his second Mangekyo ability, Amaterasu, a black flame said to burn forever.

Pain confronts Tsunade and questions her about Naruto's whereabouts. Tsunade argues with Pain about his motives, but Pain soon gets the info he needs from another source. Before preparing to depart, Pain unleashes a devastating attack on the village! Meanwhile, Naruto prepares to return to the Leaf Village, but he may be too late.