Pete suspects that his brother Adam may be responsible for their mother's illness. Meanwhile, Violet discovers quite by chance that Sheldon is dating Marla Phillips, the doctor who panned her book, and who Violet considers as her archenemy. Cooper's patient is a musical prodigy with a debilitating brain tumor.

Violet steps in to the middle of a dangerous situation.

Sheldon counsels Sam's friend, Rick, an Army veteran suffering from PTSD who harbors a secret sexual trauma; Erica and Mason are involved in a car accident that forces Cooper and Charlotte to further come to grips with their future; Violet and Pete struggle to navigate life after marriage when he finds her kissing Scott; and Addison and Jake attend a medical conference they won't soon forget.

Sheldon warns Sam that he may be in over his head when he insists on releasing Corinne from the hospital and caring for her at home; a badly beaten Scott arrives at the ER and is placed under the care of Pete; Amelia is encouraged to make a decision about her unborn child; and Jake's daughter grills him on his love life when he visits her at college. Meanwhile, Erica's health takes a turn for the worse.

Pete and Violet enter marriage counseling to help patch up their relationship; Amelia shuts down emotionally and avoids her peers upon hearing some devastating news; Addison adjusts to the new man in her life, and Charlotte and Cooper struggle with Mason when he refuses to speak to them. Meanwhile, Violet becomes suspicious of the sister of one of her patients.