Charlotte's painful memories of a horrible tragedy are triggered as Amelia continues her downward spiral; Addison takes one step closer to motherhood when she finally chooses a sperm donor; Cooper faces a difficult decision when he realizes his patient's parents have been drugging their son in an effort to control his supposed ADHD; and Pete's trust issues prevent him from repairing his fragile relationship with Violet.

Amelia’s drug addiction spins further out of control as she plays hooky from work with a new fling, starts writing pill prescriptions for herself, and has a run-in with the cops; Addison and Jake are at odds when they must make the impossible choice between donating their patient’s organs or saving the life of her healthy, unborn baby; Violet begins working at Seaside Wellness again, and Cooper, Charlotte and Mason begin to form a family bond, much to Erica’s chagrin.

The Seaside Wellness group stages an intervention for a defensive and volatile Amelia, who has resurfaced after disappearing on a 12-day drug binge with her boyfriend, Ryan. During the intervention, Amelia mercilessly attacks her friends one-by-one, and Addison, in particular, has trouble seeing her sister-in-law in her present condition.