Sheldon fears the worst when a little girl goes missing from the ER; Addison and Jake have a disagreement about one of his patients; and a new doctor joins the team at Saint Ambrose. Meanwhile, Stephanie questions Sam about his past with Addison.

A reality show centered around Sam sheds some light on issues in his colleagues' personal lives. Meanwhile, Sam's mother seeks his help after her boss falls ill; and the search continues for a girl who went missing from St. Ambros.

In this Addison-centric episode, her role as a parent is challenged when Henry's biological mother reappears and asks to be more involved in her young son's life. Meanwhile Addison reconnects with her mentor, who shares a very painful secret.

Upon hearing that he must meet with Henry's social worker during a home visit, Jake fears that an incident in his past will come to light. Meanwhile, Addison becomes skeptical of Jake's needy patient and James continues to pursue Amelia.

In an episode told from Cooper's point of view, we follow him from the moment of conception through a nasty fight with Charlotte, which inadvertently threatens the lives of their triplets. Meanwhile, Violet comforts a friend who is being advised to take her partner off life-support.

During a dark moment in his life, Sheldon finds happiness with a new woman. Meanwhile, he becomes increasingly suspicious about his patient Nick's involvement in Sarah's disappearance.

Charlotte continues to run the hospital from her bed; Mason starts acting out in school.

Amelia, now sober for more than a year and on the mend emotionally, goes on a series of disastrous blind dates set up by the other doctors at the practice.

Addison attends Henry’s court date and realizes that the judge still has some concerns about Jake’s past, Sheldon introduces Miranda to his friends, and Cooper’s efforts to secure a dream house are put on hold when Charlotte goes into labor.

Naomi returns to stand by Addison’s side on her wedding day, Cooper struggles with the hardships of being a stay-at-home father, and Violet begins a new project close to her heart, on the Series Finale of “Private Practice