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When the dead body of an asian child is discovered in a lateral river channel in Duisburg, chief inspectors Schimanski and Thanner have to investigate the case. The autopsy shows that the victim had typhus, since this could lead to a dangerous epidemic, Schimanski and Thanner had to find out more information as quickly as possible, while under pressure from the press and the public.

Schimanski is investigating the drug mafia. The trail leads to a luxurious club where political celebrities, the wealthy and the demimonde meet.

But suddenly he is standing in front of Zabou. He knows her from before, when she was still a child, his girlfriend's daughter. Back then he was like a father to her. But what is she doing here now?