As a reward for his denunciation of Martin Luther, the Pope christens Henry “Defender of the Faith,” but a brush with death causes the king to seek a solution to his lack of an heir. Princess Margaret marries the decrepit King of Portugal reluctantly, but the union is short-lived; Henry's desire for Anne Boleyn intensifies when Anne goes home to her family estate.

England's population is suffering, both from a lack of food and from a lethal plague called 'The Sweats'. As a result, King Henry feels depressed and not his usual, confident self. He starts having doubts about the future and his ability to rule the country. Fortunately for him, a change is coming up.