米查姆与奥利弗拉针锋相对，为了调查国土安全部官员遇害案，布莱斯新组建的行动组穿梭于洛杉矶的大街小巷，最终揭露出一个令人震惊的真相。

布莱斯的团队奔赴墨西哥，为获取港口货轮情报，不惜与致命贩毒集团合作执行一项危险任务。

行动组策划了一场惊心动魄的劫狱行动，以获取神秘人物沃尔切克的身份信息和藏身之处。

尚未从悲痛中恢复的小组找到了蒂莫尔诺维科夫的舅舅米哈伊尔，并设下圈套，意图引沃尔切克现身。

行动组潜入白俄罗斯领事馆，搜寻能最终揭露沃尔切克真实身份及其阴谋的机密档案。

行动组根据新线索一路追至加利福尼亚沙漠，但嫌犯不打算轻易投降。与此同时，沃尔切克悄然启动了他计划的下一阶段。

当行动组分头追查三条新线索时，总领事阿斯塔波夫的安保人员正试图以武力迫使沃尔切克放弃计划。

The team races to try and catch Volchek as he begins to deploy his weapons of mass destruction around Los Angeles.

With their leader fighting for his life and Meachum's medical condition worsening by the minute, the team finally comes face to face with the true nature of their enemy's plans as time is running out to stop him.

The task force violently confronts Volchek to save a city of millions. As the smoke clears and Meachum works to resolve his medical issues, a new threat emerges from Secret Service agent Ryan Fitzgerald.

Shepherd works to decipher the manifesto recovered at Cabin 6 while the rest of the team pursues a suspect on the run.

As another death ratchets up the pressure, the team makes a startling new discovery about their suspect.

The team zeroes in on a suspect and moves for a take-down... but soon find one of their own in grave danger.