Following the death of his fiancee Peggy at the hands of heroin smugglers, Dr David Keel vows to track down the killers and avenge his lost love. He is aided in his quest by a mysterious stranger, John Steed.

Steed has infiltrated a gang, led by Mason, which is implicated in Peggy's murder. Steed asks Keel to establish contact with a rival gang, and the doctor discovers that Vance's hitman, Spicer, has been sent to kill Steed.

Steed, investigating a number of probable arson cases, is led to the hairdressing salon of Olive and Jacques Beronne. He asks Keel to let Carol investigate the salon, but after she enters, there is an explosion from within