When an elderly woman is brought in with signs of dementia, Dr. Wolf investigates whether she's suffering from a neurological disorder or having a late-in-life awakening. Dr. Pierce grapples with a chilling discovery about one of her patients.

When an artist refuses to paint for his upcoming show, Dr. Wolf and his team must figure out why. Dr. Pierce goes into uncharted territory with a patient.

An unexpected patient crashes into Bronx General with mysterious life-threatening symptoms.

Dr. Pierce treats a patient in crisis, presenting an ethical dilemma. Dr. Wolf and Dr. Nichols disagree on how to treat a patient.