Danny and Sam get into a fight, and when Sam utters the words, "I sometimes wish I'd never met you," she finds herself in a world in which she and Danny are strangers. Worse than that, since it was Sam who encouraged Danny to check out the Fenton Portal the night he got his ghost powers, Danny doesn't have any powers! Now, Sam must convince Danny that they share a friendship and a history, and lead him back to the Fenton Portal for a second "accident" so he can again become Danny Phantom.

Sam's got a new crush: Gregor, a goth transfer student from Europe. And Danny's jealous, although he won't admit it. Instead, he convinces himself that Gregor is an undercover operative for the Guys in White, out to get Danny Phantom. When Sam finds out Danny has been spying on her, she's furious, but Danny's suspicious grows when the Guys in White show up in Amity Park. The mystery deepens as Tucker tries to help Danny uncover Gregor's intentions. Is Danny right? Is Sam truly in danger from Gregor and the Guys in White, or is Danny just jealous of Sam and Gregor's growing romance?