Danny fears he's going to cause his parents' break-up when he knocks Jack's anniversary gift into the Ghost Zone. Desperate to retrieve it, he dives into a ghostly dimension where he runs afoul of Walker, the ghost warden of a ghost jail, and is thrown into prison with every ghost he's ever caught.

Danny Fenton hates Christmas. When he accidentally destroys the only copy of a ghostly Christmas story, the book's author, Ghost Writer, makes Danny hate the holiday even more by turning him into the main character of a brand new Yuletide tale. Danny is now trapped in a scenario where everyone talks in rhyme! With his magical Quantum Keyboard, Ghost Writer creates a series of catastrophes that threaten to ruin Christmas for all of Amity Park and pins the blame on Danny. When Danny goes into the Ghost Zone to confront Ghost Writer, he is surprised to find his old ghostly enemies in a giving mood. Danny enlists them to help him defeat Ghost Writer and restore the spirit of Christmas to Amity Park and, perhaps, to his own heart.

Skulker's on a looting spree, snatching up a number of seemingly unrelated items. Unfortunately, Danny's attempts to stop him are thwarted by the well-intentioned meddling of Danny's new sidekick: Jazz. However, Danny didn't ask for -- and doesn't want -- Jazz's help, and after a series of humiliating mishaps, Danny blows up at his sister. In response, Jazz runs away from home... to Vlad's castle in Wisconsin! But it's only a ruse. Jazz soon manages to break into Vlad's inner sanctum and discovers that he has been using Skulker to collect the items necessary to upgrade the Fenton's stolen Ecto-Skeleton. When Danny arrives at the castle, Vlad makes Jazz don the improved battle suit in a no-holds-barred fight against Danny Phantom!

Sam's got a new crush: Gregor, a goth transfer student from Europe. And Danny's jealous, although he won't admit it. Instead, he convinces himself that Gregor is an undercover operative for the Guys in White, out to get Danny Phantom. When Sam finds out Danny has been spying on her, she's furious, but Danny's suspicious grows when the Guys in White show up in Amity Park. The mystery deepens as Tucker tries to help Danny uncover Gregor's intentions. Is Danny right? Is Sam truly in danger from Gregor and the Guys in White, or is Danny just jealous of Sam and Gregor's growing romance?

After an argument with their respective boyfriends, Spectra, Kitty and Ember join forces and use their powers to make all men vanish. Danny and Jack are fishing in Lake Eerie, the only place on Earth immune to the spell. Sam, Jazz and Maddie must stop the villainesses while Danny is out of town. Unfortuantely for Danny, Skulker is taking more time hunting Danny to prove his girlfriend how great hunter he is. Can Amity Park be saved without its hero?

The Fentons sell Fenton Works to the Guys in White who plan to destroy the Ghost Zone (unaware that Earth will be destroyed too) with a missile; meanwhile, Danny starts to let the rich life get a hold of him and jeopardize his friendship with Sam and Tucker.

As one of the weakest ghost in the Ghost Zone, the Box Ghost attacks with every "deadly box" he has in the human world, but is easily defeated by Danny. He then makes a plan: he will use "Pandora's Box", the most powerful box ever created, and will use the evil and deadly powers inside it to attack Amity Park. Now Danny must find the only one able to save the day: Pandora herself!