Red Chinese agent Wo Fat uses a sensory deprivation chamber to procure information from U.S. agents. Steve McGarrett, head of Hawaii Five-O, investigates the death of a close friend who appears to have drowned. Steve's knowledge about his friend and a mysterious white substance lead him into a high-level intelligence matter involving a foreign agent. McGarrett, head of Hawaii's state police force, poses as "control," possessor of the names of other agents. He allows himself to be captured and placed in the chamber; will he be able to withstand the torture?

McGarrett is caught and cocooned, and must escape this torture and shut down Wo Fat's operation.