When Michael reveals his escape plan to Sucre, Sucre chooses to be no part of it, and requests a cell transfer. Michael gets a new cellmate called Haywire.

Veronica keeps uncovering new information regarding Lincoln's case and decides she wants to work on the case full-time. When no one wants to help her on the case, Nick Savrinn (an attorney) offers his assistance and the two of them visit Lincoln.

Lincoln is worried about Michael's sanity while Michael has trouble remembering some parts of the prison schematics. Sucre has to conceal the hole in the guard's break room. Warden Pope transfers Michael to solitary after he declines his request.

In an effort to recreate the missing piece of the tattoo, Michael gets transferred to the psych ward, seeking the help of Haywire. T-Bag and C-Note have to join forces.

Everyone's ready to make their escapes across the high wire. Veronica and Nick realize they may be in over their heads. And Agent Kellerman helps Vice President Reynolds calm down before her debate.

As the escape is in progress, Warden Pope and Captain Bellick begin a search to detain the escapees. Michael and co. have to reach the aircraft fast as the police is hot on their heels. Veronica discovers a major piece of evidence that could prove Lincoln's innocence. The Vice President is worried about losing her authority.

Mahone takes an interest in the story of DB Cooper.In their quest to find Westmoreland's treasure, Michael and Lincoln travel house-to-house in Utah. Haywire's journey outside the prison walls continues. Sucre bumps into an acquaintance.

Michael, Sucre, T-Bag and C-Note claim the hidden treasure.An anxious Lincoln risks everything to get to LJ. LJ grows wary about the easy getaway. Kellerman rethinks where his loyalties lie after Sara gets to The Company's hit list. Mahone results to deadly force to get the truth out of Tweener.

In Mexico, Sucre gets a car but gets in trouble by the police. Bellick has more trouble as the new inmate as prisoners who suffered with him want revenge.

C-Note gets into a tricky situation when a robber holds up the diner he is in and demands everyone go into the storage room until the police arrive. Michael, Lincoln and Kellerman get closer to revealing the conspiracy with the help of Sara. Mahone finds a new ally in Bellick.

After taking delivery of a package from The Company, Lincoln realizes that they are deadly serious. Michael's new break out plan relies on electricity. Haywire is back from the dead, haunting disoriented Mahone. Bellick and T-Bag get special attention from Lechero.