When a Jehovah's Witness patient is admitted for treatment, Terri and Luke find themselves on opposing sides of an ethical dilemma. Bron is forced to make some difficult decisions in order to save a life when she is caught up in an armed robbery. Mitch is devastated by the unexpected death of a patient despite his furious efforts to resuscitate her. Conner scores a double date with a surprising conclusion.

Mitch is forced to confront his fears when a cancer patient refuses treatment. He embarks on a campaign to make his patient change his mind but ending up drunk and alone, he bangs on Terri's door. Steph gets starry-eyed about a possible promotion when Joan recommends Terri for a new position as her replacement. Bron gets the "relative from Hell" when she finds herself under constant scrutiny by a patient's daughter during her ward shift. Meanwhile, Jared blames Connor when Samantha's mother takes a fall and Ward 17 is finally sent a charming, polite and quick ward clerk… but for how long?

Sister Bernard again questions Terri about her commitment to All Saints and apparent lack of commitment to the Order's community house. Terri is outraged to learn that Bernard has already taken the liberty of discussing the situation with the Superior General. To Bernard's way of thinking, Terri needs to make a decision about what really is the priority in her life.

When Connor learns that his brother Greg has been admitted to All Saints, he is reticent about making contact. The pair has not seen each other for over a year and their relationship is far from rosy. Connor swallows his pride and arranges for his brother to come to Ward 17, hoping that this could be his chance to build bridges with his estranged sibling. But Greg's antagonistic behaviour is not making things easy for either of them.

A newlywed couple begins to think they are never going to make the cruise they have booked for their honeymoon. The groom has been brought into All Saints on his wedding night following an asthma attack at the reception. Just when it looks like he is about to be discharged, he suffers another attack and Mitch has no option but to keep him under further observation. Then, when the evacuation happens, it really looks as if they will miss the boat.

An unidentified male patient who attempted suicide is sent up from Emergency. He is believed to have taken a non-lethal dose of a sleeping pill. What starts out to be a straightforward babysitting job turns nasty when the patient suddenly arrests and dies. Von and Steph are in the process of laying out his body when the pathology lab puts through an urgent call to Mitch. The blood tests indicate the patient has swallowed a highly reactive agricultural chemical which has reacted with the fluid in his stomach. The dead man's body is consequently leaching toxic fumes. As a result, Ward 17 needs to be evacuated.

A disaster plan is put into action. When all the patients are removed from the ward, the staff themselves are shepherded outside and ordered to take blood from and examine each other. All are told to be on the lookout for possible side effects of exposure. Realising they are dealing very much with an unknown quantity, Steph worries that her fertility may be affected.

Bron is disillusioned about her career in the ambulance service. She is frustrated that she is unable to use a lot of the skills she acquired during her years of nursing. But while she and Ben are transporting a patient from Ward 17 to St Angela's, both her nursing and ambulance skills are required to help treat a fitting patient. This experience renews her commitment to the ambulance service and she decides to study for her Level 2 exams.