Bob Parkin is in for a lung resection and Bron has developed a soft spot for him. She faces crisis upon crises as she hands in her resignation and her dear friend's life-saving operation goes terribly wrong. Connor doubts his ability as a nurse when a deranged patient takes a dislike to him. Von finds anger and compassion when a streetkid takes an unorthodox path to find help. Jared bears the brunt of Amanda's prejudices when she finds out that he could be HIV positive.

The husband of an old friend of Steph's is admitted with an inoperable brain tumour. His wife is barely coping with the strain and it seems a blessing when he slips into a coma. Steph soon faces a moral dilemma when she suspects her friend of performing euthanasia on her dying husband. Bron returns to the Ward for a shift as an agency nurse and her exciting stories as an ambo soon wear thin with the others. Jaz finds an unexpected ally in her struggle to see Danny brought to justice. Peter is troubled by thoughts of who received his late wife's organs.

Having responded to the scene of Sophie's car accident, Ben is having difficulty coming to terms with the aftermath of treating people he knows. Sophie and her children have survived the head-on collision resulting from her impaired driving but her friends are even more shocked when her desperate actions the night before come to light. Refusing to lose custody of her children to the man who raised her husband, Sophie confronts her father-in-law from her hospital bed putting Terri and Peter in the middle of a siege situation that will change eveyone's life. Meanwhile, Bron's fundraising netball game disintegrates when some personal agendas come into play on the court and Von's New Year's resolution seems destined to go up in smoke. A comment in the OR results in a nurse filing a report against Luke for negligence.

Terri struggles to deal with what has happened to her friends Sophie and Peter. Bron learns about the hierarchy in the ambulance organisation when she finds herself under the supervision of a strict training officer. Having been confined to desk work while recovering from his Post Traumatic Stress, Ben confronts his demons when he resuscitates a girl at a local shopping mall. Jared and Samantha's blossoming romance is tested when they disagree on a patient's diagnosis. Despite downplaying the honour publicly, Von is secretly thrilled to be chosen as Employee of the Month. Connor ignores pleas to seek treatment for his bad back — until he sets eyes on Lily, the gorgeous acupuncturist.

A busy day on the ward turns to chaos when the Health Minister is brought in as a patient. Experiencing first-hand the demands on the public health system, the Minister is sympathetic to the needs of the nursing staff but can offer nothing more than an expression of support. A lack of beds on the ward means a patient is left to recover from her operation on a trolley in the corridor. Despite protests from Steph, Luke is authorised to send the patient home early — a decision that has disastrous consequences. Terri struggles to help a Peter cope with his disabilities. Discouraged by his prognosis for recovery, Peter has difficulty adjusting to life in the hospital as a patient. Connor's visit to Lily, the beautiful acupuncturist, has embarrassing repercussions.

Mitch Stevens' unorthodox doctoring style brings tension — and humour — to Terri's ward. He steps on many toes as he goes but his decisions prove to be life-saving. Ben's first day back on the job as a paramedic brings unanticipated challenges for Bron when a young mother suffers an horrific tractor accident. Samantha O'Hara suffers a crisis of confidence when she makes a diagnostic mistake which affects her budding relationship with Jared while Connor becomes the unwitting pawn in a lapdancer's manipulative game. Terri steps in to care for Peter when he dismisses his homecare nurse.

In an episode about dependence between friends, partners and workmates, dependence takes the form of teamwork, friendship and co-operation for some, while for others it is a reminder of a lack of independence. A street kid holds Mitch hostage in an attempt to abduct his junkie friend from Ward 17. Bron and Ben are faced with a complicated premature childbirth which tests Bron and brings up painful memories for Ben. Terri tries to help Peter cope with his trying day as a hospital out-patient. Connor suspects a budding romance between two patients. Von's Employeee of the Month honour garners her more unwanted attention.

The ward is thrown into turmoil when a patient who claims to be psychic says she spoke to the ghost of Sophie Williams who comforted her through the night. The woman's claims and the associated media coverage keep the staff on edge but the arrival of one young visitor pushes Von over the edge. Terri finds herself torn between her duty as a nurse and as a nun when she tries to help a young patient confused about his sexuality. Bron and Jared find life steamy at home when Connor has a house call from Lily. Peter gets more than he bargained for when he wallows in self-pity once too often.

Peter is pushed to the limit when his life seems to be falling apart and he considers taking drastic measures. Samantha and Jared suspect a son of drugging his father but their differing approachs to the case serves to highlight their different backgrounds. Ben decides he can't wait for Steph to come around to the idea of having children and makes a momentous decision. While running the ward, Steph sends the staff mad when she takes her study too seriously. Jared and Samantha's relationship is made public, much to Jared's surprise. Luke leads a group of students on rounds and Mitch find the proper motivation to aid a patient's recovery.

Ward 17 is thrown into turmoil when Danny Bucknell is admitted as a patient to recover following a suicide attempt. It's a guilt-stricken time for Peter when his son goes missing and he comes to the realisation that it is time he focused on being a good father again. When Jaz's final attempts to make him admit to the rape fail, she makes an important life decision and announces her resignation with the intention of going back to school. Bron and Ben disagree about how best to handle the situation when they attend to a man who has been trapped under a fallen tree. Mitch picks up an interesting case from Emergency and Connor has the day from Hell when Joan Marden, the Assistant Director of Nursing, comes under his care.

Emotions on a personal level are running high when Peter shocks his friends by revealing he has resigned from All Saints, leaving Terri feeling lost and alone. Bron finds it hard to stick to ambulance procedures when a young security guard that has been shot during an armed robbery at Cougars is a friend. A young bashing victim tells Steph a secret, leaving her to decide whether to tell the police or not. Samantha finally meets Jared's mother but her hopes for making a good first impression are quickly dashed. Meanwhile, a new temporary ward clerk irritates the staff.

Jared and Samantha's relationship is strained after he finds himself unknowingly caring for her mother when she is admitted to Ward 17 for a hip replacement and he finally learns why Sam has been hiding details of her personal life from him. Ben and Bron clash when she doesn't follow procedure while dealing with a heroin-addicted mother at the scene of a car accident. Forced to file a report on the incident, Ben then accuses Bron of taking advantage of their friendship. Von finds herself in the middle of a love triangle as she tries to keep a patient's wife and mistress from meeting one another. Luke's patient, a recovering drug addict, refuses pain medication after surgery leaving Terri to seek out alternative treatments. Meanwhile, Connor celebrates a birthdayand another temporary ward clerk joins the team.

Mitch is forced to confront his fears when a cancer patient refuses treatment. He embarks on a campaign to make his patient change his mind but ending up drunk and alone, he bangs on Terri's door. Steph gets starry-eyed about a possible promotion when Joan recommends Terri for a new position as her replacement. Bron gets the "relative from Hell" when she finds herself under constant scrutiny by a patient's daughter during her ward shift. Meanwhile, Jared blames Connor when Samantha's mother takes a fall and Ward 17 is finally sent a charming, polite and quick ward clerk… but for how long?

It's a heartbreaking time for Samantha when her mother does not respond to treatment for pneumonia and a wound infection. She finds she cannot cope with her impending death and Jared is shocked when she drops a bombshell on him. When an eager young bystander rescues an alcoholic from a blazing warehouse, Ben suspects foul play while Bron learns that ego is a dirty word. Meanwhile, Mitch uses his voodoo skills to help a deluded patient.