A romantic escapade goes horribly wrong when a young couple are involved in a motorbike accident, and the tragic events of the night leave the staff of St Aiden's struggling to heal more than just a broken heart. Dr. Ormerod grows suspicious when one of his patients is uneasy about returning home, but an investigation by Matron soon reveals the reasons for his reluctance. Meanwhile, Ken and Alun face trouble when a plague of rodents looks set to close down the hospital - but is local rogue Claude Greengrass really the best person to ask for advice?

Claude Greengrass causes a kerfuffle with a coffin containing the remains of his deceased sister and a mysterious phone call only serves to raise suspicions. Jill Weatherill has trouble with a patient who refuses to accept her condition, while Dr. Cheriton panics when he arrives at the scene of an accident bereft of vital medical equipment.

A serious coach crash throws the Royal into chaos, and for one member of the staff, the incident proves exceptionally traumatic. Cheriton has a bombshell for Nurse Taylor.

Ormerod rushes to help following a boating accident, but realises he's been sent to the wrong location, and when he finally arrives at the disaster scene, his efforts to save a man's life prove futile. On returning to the hospital, he angrily chastises Lizzie for the misinformation - only to realise he was too hasty in blaming her. Can he make amends? Meanwhile, PC Ventress comes to the Royal with two men who had been fighting over a girl, and one promptly collapses due to a brain haemorrhage. Weatherill faces a testing time when she helps deliver a baby which is tragically stillborn and nurse Meryl reveals she suspects she may be pregnant.