After digging up the skeletal remains of a young girl, the investigation points to a convicted serial killer on death row. The team follows cryptic clues that lead to another body, an accomplice, and a victim who may still be alive.

Booth and Brennan investigate a death due to an explosion in a Miami hotel. The clues lead to foreign diplomats with diplomatic immunity.

When the skeletal remains of a federal prosecutor who disappeared five years earlier are found in the desert outside Las Vegas, the team suspects it to be tied to the mob. Booth and Brennan go undercover as Vegas high-rollers in an attempt to uncover the mystery, Booth risks his life.

While investigating the death of a film student who was working on a documentary about the legend of a headless witch who haunted the woods in the 1700s, Brennan develops a strong bond with the victim's brother.

The notorious serial killer, Howard Epps, sets his prison cell on fire as part of a daring prison escape. Brennan is his target and her entire team is placed in danger.

Booth and Brennan investigate the case of a partial skeleton found in cement. Booth thinks a member of a crime family is responsible.

When Angela draws the face of an old woman to go with the decomposed skeleton of someone much younger, they soon learn the victim had Progeria, an aging disease. Booth and Brennan investigate to discover who would want to kill such a fragile person. Meanwhile, Hodgins and Angela's walk down the aisle doesn't go as planned.