A runner struggles to regulate body temperature while training; Boris' decline may not be related to the disease.

Hank struggles to cope with Jack's illness; young brothers keep Hank busy; Evan teams up with Boris' cousin.

Hank embarks on a fresh start with his medical practice and separates from his brother Evan, who also starts his own venture. As Divya attempts to reconcile the brothers, HankMed teams up once more in the face of a Hampton's emergency.

When Jill’s chess-obsessed nephew gets kicked out of camp for fighting, Hank realizes Luke may be suffering from more than just teenage hormones. Evan courts a young, lonely heiress for his new client roster, and Divya – caught between the brothers -- faces an impossible choice.

Hank has a realization about his relationships; Divya's fling takes a surprising turn.

Hank gets back to work after recovering from surgery and treats a woman whose fund-raising efforts may be harming her health. Elsewhere, Jeremiah helps HankMed meet demand; a potential new client catches Evan off guard; and Divya receives surprising news.

Hank's investigation into Boris's death leads him to a shocking discovery; Divya and Jeremiah check out a Savannah hospital; Evan's crusade takes an unexpected turn.

Hank becomes embroiled in a plot while in Monte Carlo; Divya and Jeremiah treat mysteriously ailing firemen; Paige and Evan search for a new place to live.

An actor wants to shadow Hank in order to prepare for a role. Divya performs a genetic test on a royal patient. Evan accidentally takes his new motto of transparency a step too far. Paige embraces chaos during a home renovation project.