Hank embarks on a fresh start with his medical practice and separates from his brother Evan, who also starts his own venture. As Divya attempts to reconcile the brothers, HankMed teams up once more in the face of a Hampton's emergency.

When Jill’s chess-obsessed nephew gets kicked out of camp for fighting, Hank realizes Luke may be suffering from more than just teenage hormones. Evan courts a young, lonely heiress for his new client roster, and Divya – caught between the brothers -- faces an impossible choice.