When Allison Moore, the owner/head chef of a trendy Hamptons restaurant suffers a stroke, Hank attempts to save her from potential long-term damage, but she goes missing before treatment is administered. And on the day that Hank had previously planned to get married he spends time with Jill.

Hank and Divya treat the heir of a famous inventor whose desire to distance himself from his father puts him in harm's way. Meanwhile, Jill's job at Hamptons Heritage is threatened when her mentor starts proceedings to have her fired.

Hank is worried that a new patient had previously been misdiagnosed, and wants to get to the bottom of the case. Meanwhile, Divya and Raj take dance lessons in preparation for their wedding, but they end up as patients themselves.

HankMed saves the passengers of a toppled Jitney; Divya deals with the fallout from her broken engagement; Jill returns with news.

An undercover DEA agent believes she is suffering from meth toxicity.

Hank treats a cop with a rebellious teenage daughter; Evan and Paige adjust to their new home; HankMed receives an offer from a patient; the changes in Divya's life may be more complicated than she expected.

The chef at Ray’s new restaurant seems to be getting drunk on the job, but Hank believes it’s not just a matter of hitting the bottle. Divya treats a NASCAR crew chief who channels his anxiety into an unexpectedly dangerous habit. Evan’s friendship with Ray helps him find a promising space for HankMed’s new lab, but Jeremiah has concerns about the location. And while Hank tries to get Emma to think about her future, Divya makes an important decision about her own.

Hank helps a TV host. Evan and Paige buy get some unexpected news. Divya saves a young skateboarder.