"Trauma" is an intense, action-packed look at one of the most dangerous medical professions in the world: first responder paramedics. When emergencies occur, the trauma team from San Francisco City Hospital is first on the scene, traveling by land, by sea or by air to reach their victims in time. From the heights of the city's Transamerica Pyramid to the depths of the San Francisco Bay, these heroes must face the most extreme conditions to save lives -- and give meaning to their own existence in the process. In this initial installment, tragedy hits close to home, and the lives and paths of the team are forever changed.

The team responds to a major accident when a car loses control and crashes into a local street fair. Meanwhile, Nancy gets a new partner, and Rabbit teaches Marisa a lesson.

Rabbit has a breakthrough in therapy that reveals a traumatic event from his past. Meanwhile, Nancy and Dianas difference of opinion puts a patients life at risk. Elsewhere, Tyler and Boone consider their futures, as Glenn reaches a career milestone.

In the process of gathering stories for his book, Glenn finds himself discussing unusual calls with his work mates and ends up hearing much more than he imagined. Elsewhere, Tyler's dad comes to town for a visit.