The tables have turned as Nancy and Glenn find themselves on the other side of the trauma. Meanwhile, Boone's priorities on the scene are called into question. Elsewhere, Rabbit has a surprising reaction while treating a patient.

A wedding celebration at sea is interrupted by a high-speed boat collision. As the team quickly rushes to their aid to treat the victims, things get lost in translation. Meanwhile, Nancy takes time to reconnect with her family. Elsewhere, Marisa comes to the aid of those close to her heart.

Thanksgiving travel gets dangerous when a packed commercial airliner must make an emergency landing that goes terribly wrong. Meanwhile, Nancy finds herself reluctant to spend the holiday with her family. Elsewhere, Boone and Tyler respond to an unusually common Thanksgiving emergency.