After developing a crush on Lisa (Lisa Tucker), Michael becomes too nervous to perform in the Open Mic night, causing him to throw up on her and making Lisa like another guy. Can Michael still get the girl of his dreams? Meanwhile, Logan and Chase are having a go-kart race.

Zoey's date gets put on hold when the girls are quarantined in their room because Quinn made her own germ and spilled it all over the floor. Quinn calls some biology experts and is told that they have to stay in their room in order for the germ not to spread throughout the campus. While Zoey, Chase, Lola, Michael, Quinn, and Logan are quarantined, they all have problems. Meanwhile, Quinn thinks Mark is cheating on her.