The gargoyles awaken to find nearly all of New York City's denizens turned to stone. A millennium before, a young man named Macbeth must decide how much he's willing to sacrifice for love.

While Xanatos works to break the spell, the story of Macbeth continues, as the lord must take up arms against his brother when the Weird Sisters foretell his ascension to the throne of Scotland.

The plan to end the spell is sent into motion, but Demona makes preparations to stop it. In the past, MacBeth must decide if his alliance with the gargoyles is worth a war with England.