Monk heads to Los Angeles to help the father of his late wife solve a very puzzling mystery on a game show.

Monk takes a new medication that alleviates the symptoms of his obsessive-compulsive disorder but impairs his ability to solve crime.

When all signs in a murder investigation point to deceased Kung Fu movie star Sonny Chow, Monk must find the real culprit.

Monk goes toe-to-toe with a popular radio shock jock who is suspected of killing his wife.

When Monk is arrested for murder, he escapes the custody of a small-town sheriff and becomes a fugitive on the run.

While everyone mourns Monk's "death," Monk searches for the truth that will clear his name.

As Monk and his friends watch a TV news magazine piece on the solution of his hundredth case, he realizes that one of the victims was murdered by a different killer.

Monk is called to a crime at the location where he first heard the news of his wife's murder and begins the most important investigation of his life.

Monk pursues the killer of his wife.