Fifteen designers arrive in New York and are asked to create an outfit in just two days using only materials found in their apartments.

The designers are paired into groups to design and create a gown for Miss USA, Tara Conner, to wear for the Miss Universe pageant. The designers have $300 and two days to complete their designs.

The designers are informed that they'll be creating an evening outfit based on a story inspired by a tiny dog. The designers must also design outfits for the dogs to wear. They have $150 and two days to complete their looks.

The designers, in teams of three, are asked to design a three-piece look that embraces the INC (International Concepts) brand. The winning design will be manufactured, produced, and sold at Macy's stores. The teams have $100 and two days to complete the challenge.

The designers face the challenge of modernizing a look for a famous "fashion icon:" Cher, Farrah Fawcett, Pam Grier, Audrey Hepburn, Katharine Hepburn, Madonna, Marilyn Monroe, Jackie Onassis, Diana Ross, or Twiggy. They have $150 and two days to complete their designs.

At the Waste Management Recycle America Center, each designer is given 30 minutes to fill as many bins as they desire with recyclable materials. They must create an outfit from these materials, in one day, with an additional $25 for art supplies.

The designers are asked to create an outfit for an "everyday woman" …each other's mothers and sisters. They have $150 and one day to complete the challenge.

The designers are tasked to create an "international jet-set" outfit. They will then be flown to Paris to model the wearability of the garments. They have $75 and one day to complete the look.

While in Paris, the designers' next challenge is to make a gown employing haute couture techniques. They have 300€ and two days to complete the challenge.

Eliminated designers who have won at least one previous challenge are given a chance to get back into the competition. The designers are asked to create a cocktail dress using only black and white fabrics. They have $100 and one day to complete their design, with the stipulation that they must use all of their purchased fabric.

The designers are asked to create an outfit that expresses "their specific point of view." They must also stage a photo-shoot with their models and find three words that best express who they are as designers. They have $250 and two days to complete the challenge.

The cast of Season 3 reunites to recap all the gripes, drama and other shenanigans which were only seen by those behind the scenes. One of the designers wins the first ever "Fan Favorite" award, along with a check for $10,000.

Each of the remaining designers is given two months and $8000 to design a 12-piece collection for Olympus Fashion Week. In the interim, each gets a special visit in their hometown from Tim Gunn.

In the conclusion of the finale, the remaining contestants ready their collections for the runway. Then they present their lines to industry insiders at Olympus Fashion Week.

The 16 new contestants are introduced and face their first challenge. The designers are asked to create a look using only materials purchased from a grocery store. They have $75 and one day to complete their outfits.

The designers are asked to create a cocktail dress, using environmentally friendly or conscious fabrics, with their models as their clients. They have $75 and one day to finish their garments.

The designers are tasked to create a look inspired by the nightlife of New York City. They have $100 and one day to complete their designs.

The designers must create a women's wear look for the 2008 Summer Olympics Opening Ceremonies. They have $150 and one day to complete their designs.

Brooke Shields gives the designers their next challenge, to make an outfit she will wear on her television show Lipstick Jungle. They pitch their ideas to Shields, who chooses half of them as team leaders to be paired randomly with the remaining contestants. The designers have $150 and one day to complete their looks.

Former contestant Chris March returns to give the designers their next challenge: make an outfit for a drag queen. They have $200 and two days to complete their designs.

The designers are asked to make an outfit from the spare parts and raw materials of a Saturn hybrid car. They have four minutes to collect their materials and one day to complete their outfits.

The designers are taken to the offices and design showroom of fashion living-legend Diane von Fürstenberg. Their challenge is to create a look for her Fall 2008 collection, inspired by the movie A Foreign Affair. They have 15 minutes inside von Fürstenberg's sample room to select fabrics and one day to complete the outfit.

The designers are paired up with eliminated contestants and asked to create an avant-garde garment inspired by one of their two astrological signs. They have $250 and one day to complete the look.

The designers are assigned recent college graduates and are tasked to give them a fashion makeover to help them enter the workforce. Each designer was to gear their look to their client's specific profession, while keeping their individual style. They have $100 and two days to complete their look.

The contestants are given the task of designing for each other, inspired by different genres of music. They have $150 and one day to complete the challenge.

The contestants head to the New York Botanical Garden to design an evening gown inspired by nature. They have $250 and two days to complete their dress.

The remaining designers are given two months and $8000 to design a 10-piece collection, plus a wedding gown, for Fashion Week. In the interim, each gets a special visit in their hometown from Tim Gunn. Back in New York City, the designers are given one more task, create a bridesmaid dress to go with their wedding gown.

In the conclusion of the finale, the remaining contestants pare their 12-piece collections down to ten. Then they present their lines to industry insiders at Fashion Week.