Live from New York, it's... Amy Poehler!Sketches include "Hardball," "Urigro," "The NFL on CBS," "Frontline: 2007 Year in Review" (cartoon), "The First Person in History to Dance," "MacGruber" (three parts), "Two A-Holes at an Adoption Agency," "Common & Blizzard Man," "The Unicorn Forest," "Nurse Nancy" (film), and "Lansford Brothers & Associates."AFI performed "Love Like Winter" and "Miss Murder."

Chance the Rapper hosts with musical guest Eminem.