The Sliders arrive on a world where virtual reality is a normal part of life. After Maggie is injured in an explosion, she awakens in a hospital to find they have missed the slide. The only way to go is to build a new timer, but is everything what it seems?

The vortex splits the Sliders up and they only have two hours before the slide. Quinn tries to contact the others by appearing on the world's most popular show: Lipschitz Live. Meanwhile, Colin is mistaken for his double and betrothed to a woman as part of a business deal.

The Sliders arrive in a barren wasteland, where the timer is inoperable. Worse yet, they find themselves forced to take part in a never ending battle between Kromaggs and soldiers from Quinn's home world, who are guarding a mysterious bunker.

The Sliders arrive on a world where millions play in highly realistic arcade simulations. Rembrandt and Mallory take part in separate simulations, until they discover Maggie and Diana have been forced to play characters in these simulations, where each "death" experienced is real.

The Sliders arrive in the middle of a rally, surprisingly being held in their honor. They learn they are the subjects of a religion called Slidology, founded by a man with psychic abilities. He has been following their adventures and warns that on their next slide, they will all die.