The personalities of Shredder and Splinter are switched when a device is accidentally activated during a battle between the Turtles and their enemies. As Shredder plans the Turtles' demise and Splinter plans on how to get back to his body, everyone else is clueless.

Aliens abduct Donatello and Rocksteady.

High ranking corporate executives are kidnapped by men in business suits. The Turtles don't get involved until they learn that one of these corporations is the world's largest suppliers of pizza.

Splinter suffers amnesia as the Turtles try to remind him that he is the true leader of the Foot Clan.

While watching video tapes of old battles, Raphael sees a mystery person spying on them. While the Turtles investigate, an alien warlord named Dregg sends his TechnoGansters to steal all the gold on Earth.

April contacts the Turtles to let them know that Dregg has landed on Earth and is preparing a press conference. The Turtles rush to meet April at the Park, where they hear Dregg announce his friendly intentions and offers the world his molecular converter.