After Joan stands up for one of her classmates being bullied, an embarrassing picture of Joan, taken with a picture phone, is rapidly spread around school. God instructs Joan to join the band. Will must deal with an elderly driver who accidentally killed several people.

When the hospitalized Joan is diagnosed with Lyme disease, she begins to question if she's been seeing God or merely experiencing the hallucinations that can be symptomatic of her condition...

Upon hearing that Joan may have been suffering from the symptoms of Lyme Disease for months, a somewhat relieved Will and Helen believe this news may explain Joan's mood swings and atypical behavior, while a concerned Adam wonders if Joan will be different upon her recovery. Meanwhile, the hospitalized Joan experiences a crisis of faith -- and considers revealing to someone close to her that she's been talking to God. In separate circumstances, Helen and Will begin to rethink their belief systems after, respectively, experiencing spiritual dreams and miraculous events.

After being prodded by Judith to go on a real date, Joan and Adam nervously prepare for a romantic night at a fancy French restaurant. Little do they know that Judith has subsequently made some misguided plans for herself for that evening, which later causes the guilt-ridden Joan to wonder if she could have prevented her friend's misfortune.