When a series of mysterious disintegration deaths occur in Pittsburgh, the team discovers that the artifact responsible, Joshua's Horn, has ties to Helena's time as an agent in 1893.

While Pete and Steven check out a life-threatening incident at a renaissance faire, Myka agrees to help Claudia revive her comatose sister. However, they discover that doing so has unexpected consequences that threaten the warehouse and everyone in it.

Pete's former girlfriend Kelly Hernandez asks him to help her find her missing grandmother, and the trail leads into a cancelled telenovela. Meanwhile, Artie forces Claudia to go with Steve to investigate the case of a college student of whose spine broke in the middle of a classroom presentation.