On assignment to protect the daughter of a crime czar who's agreed to testify against mob bosses Starsky and Hutch must drive her back home from San Francisco pursued by ruthless killers all along the way

Starsky and Hutch, along with three other Detectives, are involved in a large drug bust, where pure cocaine with a street value three million dollars is seized. But following the successful raid, the detective duo come under suspicion when $1m worth of the drugs disappear. They have 48 hours to clear their names.