When a young boy blames himself for the death of his friend, Brenda must tread lightly to get to the bottom of the case. Complicating matters is the deceased child's mother, who offers up accusations of her own.

The PHD must deal with a case of mistaken identity in order to get to the bottom of an investigation. While they're busy with the case, Brenda is involved in a different case: Pope's divorce. After being called to testify, Brenda finds that both her career and reputation are on the line.

Leaving the scene of an accident to get to a multiple homicide scene, Brenda finds herself unable to drive the streets of L.A. which she worked so hard to learn. Once she gets to the crime scene, she and the PHD are faced with another challenge: the murdered bodies are nowhere to be found. In order to solve this case, they must first search for the victims before they can hunt for the killer.

Once again, the PHD finds themselves wading through suspects in the murder of the star witness in a capital punishment case. Meanwhile, Pope's angry ex-wife, spills the beans about Brenda to her team and Fritz begins to wonder how she really feels.

Brenda and Fritz have a hard time agreeing who is in charge when an informant's wife and and FBI agent are both murdered. When the killer's identity is uncovered, the PHD finds themselves under attack.

Resulting from the showdown in the murder room, Brenda finds herself taking some involuntary time off. When she is asked to help a friend solve a murder that is linked to a terrorist group, Brenda works to find the killer and still keep it under wraps.

While working with the CIA, who also wants their hands on this suspect, Brenda realizes that she was given false information, and wonders if she's been set up. To prevent herself and the PHD from falling prey to a sinister plan, Brenda must untangle a web of lies to determine who she can trust before it's too late.

Brenda and the team investigate the grisly slaying of a family, and the only survivor is the drug-addled teen son. Meanwhile, a financial crisis rocks the LAPD, bringing about budget cuts and possibly Provenza’s early retirement. Meanwhile, Fritz hopes to move into a new house with Brenda.