A seemingly routine murder investigation by the LAPD Robbery-Homicide Division is interrupted by the arrival of Deputy Chief Brenda Johnson, the new head of the LAPD’s Priority Murder Squad. An outsider from Atlanta in her first week of service, Brenda has already begun to face the resistance of long-time high-ranking officers and only her assistant, Sgt. Gabriel, seems willing to try to work with her.

Brenda and the team must investigate the murder of high-profile model Heather Kingsley, who dies as a result of nicotine poisoning. As Brenda investigates, she is drawn into the world of celebrity beauty, where illusion is everything, and the standard high.

Brenda must fight for justice for two Russian prostitutes murdered by the illegitimate son of a Russian mafia figure. As she does, she confronts her own prejudices, and discovers the justice for these women is scarce in a world dominated by men.

Brenda and the Priority Homicide Team investigate a sniper who is killing gang members in and around MacArthur Park. Offering assistance is an ex-Army colonel who believes the sniper to be his son. As an all-out gang war looms, Brenda tentatively accepts his assistance.

Brenda enters the high-stakes world of pharmaceutical research, when a drug trial for new anti-addiction medication lead to the death of one of the principal investigators. Nothing is quite as it seems as she investigates the high-powered president of the drug company sponsoring the trial, the seemingly easy-going psychiatrist and the teenaged participants in the study.

Brenda finds herself the unexpected victim of violence against women when she investigates the murder of a congresswoman's daughter. At first, it appears the victim was engaged in sexual activity online that included an invitation to violence.

A judge is murdered in Griffith Park and Brenda's investigation takes an unexpected twist when her best witness, or perhaps her prime suspect, is his teenage son with autism. Challenged by the boy's behaviors, but convinced he has the clue to unraveling the case, Brenda must try to understand him in order to learn what he knows.

When a gay man is murdered, seemingly the latest victim of a string of hate crimes, Brenda must confront prejudices inside and out of the LAPD. Meanwhile, Flynn and Taylor step up their efforts to undermine Brenda once again, but with unexpected effects, as the team begins to rally around Brenda.

The murder of an adolescent girl from Mexico, found dead in the Los Angeles River, proves difficult and painful for Brenda and her team. At first, a known sex-offender seems the likely candidate, but questions arise about why the girl and her mother were brought to the US, leading the investigation in another direction.

Three wealthy, spoiled and unruly children become the target of Brenda's investigation when their stepmother is murdered and the family butler seemingly commits suicide shortly thereafter. Riding heard on the trio is their family attorney, who cleans up their messes and provides them with alibis.

Brenda finds herself at odds with the FBI in a struggle to gain control of the murder investigation of a well-known businessman. Deciding to work in tandem, Brenda finds herself working directly with Fritz, who was assigned to the case.

Brenda and her team must find not only a killer, but also identify the killer's victim when a deranged, homicidal madman is set free due to mistaken identity. While trying to make sense of an array of complexities in this unusual matter, the case takes an even darker turn when Brenda becomes the center of the psychopathic killer's attention.

An unnamed source files a grievance against Brenda in the midst of a high-profile investigation of a murdered L.A. filmmaker. With her career on the line, Brenda is skeptical of Chief Pope's intentions when he volunteers to help. In classic Brenda style, she spurns the accusation and the PHD team comes together to act in unison, sending shock waves through the entire department.

Brenda and her team race against the clock to get to the truth, as things don't add up when an LA cop turns up dead. Meanwhile tension increases between the Priority Homicide Division and the Robbery-Homicide Division.

When a juror in the trial of an infamous mobster is found dead, Brenda and the Priority Homicide Division find that their involvement in solving the case may be affecting the jury's final decision. Complicating her personal life, Brenda faces another new challenge: a surprise visit from her mother.

Things are not as they seem when Brenda and the team investigate the accidental murders of three college students caught in the middle of a gang shootout. Brenda must also continue her attempts at keeping her relationship with Fritz under wraps while her mother remains in town.

Brenda and the PHD investigate a high-profile case when a woman is brutally murdered at L.A.'s trendiest restaurant. On the home front, Brenda tries to keep a low profile as she closes in on her 40th birthday.

Brenda finds herself involved in a cover-up of her own when she helps the PHD investigate a non-priority case. Why? Because the deceased woman was found in Provenza's garage...Once again, the team finds themselves racing against the clock before the LAPD brass discovers what they're up to. Will Brenda be able to protect her team and their hard-earned trust?

Brenda and the team find themselves wading through a long list of suspects when a celebrity photographer takes a fatal fall from his hotel room balcony. In the meantime, Brenda starts to feel like Fritz is behaving strangely, making her realize that superstars may not be the only ones who have secrets to keep.

When a few body parts of an adult film star are found in a dumpster, Brenda and the team must scramble for more pieces to solve this puzzle. Once they begin putting things together, the suspect list seems to get longer. Adding more questions to her life, Brenda also finds herself making a potentially life-altering discovery.

When the drowned bodies of a mother and daughter are found by fishermen, Brenda and the team must determine if the apparent suicides are more than that. Following a strange coil of discoveries, the most surprising revelation that surfaces is one about the killer.

When a young boy blames himself for the death of his friend, Brenda must tread lightly to get to the bottom of the case. Complicating matters is the deceased child's mother, who offers up accusations of her own.

The PHD must deal with a case of mistaken identity in order to get to the bottom of an investigation. While they're busy with the case, Brenda is involved in a different case: Pope's divorce. After being called to testify, Brenda finds that both her career and reputation are on the line.

Leaving the scene of an accident to get to a multiple homicide scene, Brenda finds herself unable to drive the streets of L.A. which she worked so hard to learn. Once she gets to the crime scene, she and the PHD are faced with another challenge: the murdered bodies are nowhere to be found. In order to solve this case, they must first search for the victims before they can hunt for the killer.

Once again, the PHD finds themselves wading through suspects in the murder of the star witness in a capital punishment case. Meanwhile, Pope's angry ex-wife, spills the beans about Brenda to her team and Fritz begins to wonder how she really feels.

Brenda and Fritz have a hard time agreeing who is in charge when an informant's wife and and FBI agent are both murdered. When the killer's identity is uncovered, the PHD finds themselves under attack.

Resulting from the showdown in the murder room, Brenda finds herself taking some involuntary time off. When she is asked to help a friend solve a murder that is linked to a terrorist group, Brenda works to find the killer and still keep it under wraps.

While working with the CIA, who also wants their hands on this suspect, Brenda realizes that she was given false information, and wonders if she's been set up. To prevent herself and the PHD from falling prey to a sinister plan, Brenda must untangle a web of lies to determine who she can trust before it's too late.

Brenda and the team investigate the grisly slaying of a family, and the only survivor is the drug-addled teen son. Meanwhile, a financial crisis rocks the LAPD, bringing about budget cuts and possibly Provenza’s early retirement. Meanwhile, Fritz hopes to move into a new house with Brenda.

The body of a long-dead murder victim is uncovered along with Lt. Provenza’s business card, setting off the squad’s search for his identity and killer.

At a retired cop’s funeral, Lt Provenza and Lt. Flynn discover something quite unexpected along with the corpse.

A recently released sex offender is accused of kidnapping a child, and with time running out, Det. Gabriel makes a startling choice.

An old man’s confession to seven murders leads Deputy Chief Johnson to investigate the sudden and unnatural deaths at his nursing home.

Brenda and the PHD investigate the murder of a personal trainer who was involved with the wife of a possessive husband with a temper. Complicating the investigation, their only witness is the man's frightened valet, who also has OCD.

When two Catorce gang members are shot to death, Brenda and her squad must solve the murders before a gang war erupts. Meanwhile, Brenda has her own personal health scare when she finally visits the doctor.

It looks to be the return of a serial killer when two bodies turn up dead. With the knowledge that he kills in sets of three, Chief Pope charges Brenda and her squad to hunt down the killer before the third victim is taken.

In an effort to get good PR for the department, Deputy Chief Johnson takes a journalist on a ride-along, but when the Crown Vic is targeted and shot at, Brenda is forced to live under 24-hour police protection, while being the key witness in the case she must solve.

When a Chinese business woman is found dead on the tour bus she and her husband operate, Brenda and the squad must dig deep to investigate her past life.

A car belonging to a Department of Homeland Security employee is found wrecked at the bottom of Mulholland Drive. Priority Homicide is brought in to uncover the details surrounding the driver’s death, but the investigation leads Brenda a lot closer to home then she expected.

Deputy Chief Johnson’s investigation into a famous Hollywood divorce attorney found floating in his swimming pool is under heavy scrutiny. Meanwhile, Fritz and Brenda are trying to consolidate their bills and Brenda discovers a secret Fritz has been keeping.

Still experiencing the strain of her case, Brenda finds herself under another time crunch when she must disprove a questionable alibi within 48 hours to prevent the investigation from falling flat. As Brenda searches for the truth in her case, she discovers some inside information that may have an unfortunate effect on her relationship with Fritz.

Brenda finds an opportunity to visit home when she attempts to track down a witness who disappears to Atlanta. Unfortunately, once she finds the witness, her holidays with family take on a whole new meaning.

Returning to L.A. proves to be a challenge when Brenda's witness remains hesitant, causing her to be creative. The fallout left behind in Atlanta leaves Brenda's parents picking up the pieces while Fritz becomes buried underneath all the stress.

When a massive fire breaks out in Griffith Park, Priority Homicide is on hand to help. Meanwhile, Brenda and Fritz are living in a small apartment and getting on each other's nerves.

Brenda and the team must determine if a murder was revenge or mere coincidence when a recently released murderer turns up dead, the victim of a hit-and-run. As usual, Brenda's personal life isn't much better: she must deal with a recently incapacitated Fritz.

Brenda suspects something more than suicide when a high-school girl is found hanged in her bedroom, and the investigation uncovers a ruthless sexual game being played at a private school.

A man wearing a surveillance wire is shot to death at point blank range in downtown Los Angeles, while interpersonal relationships on the squad force Brenda into a corner.

Provenza and Flynn lose the evidence in an attempted murder case when Provenza's car is stolen.

When a 12-year-old disappears, Brenda must decide whether to treat him as a runaway or a missing person.

Det. Julio Sanchez' little brother Oscar is shot and killed, leaving Julio beside himself with grief and seeking his killer any way he can, which threatens the investigation.

Brenda and the squad investigate the murder of a hair stylist and Brenda's parents stop in for a visit on their way to Alaska.

When an FBI informant is the prime suspect in the deaths of two Tijuana police officers, Pope, Taylor and Brenda must deal with a public relations mess when a newspaper prints an unflattering story about Priority Homicide.

The newly renamed Major Crimes Division investigates the death of a teenager that may be related to a planned massacre.

Brenda and the team investigate an apparent suicide that the medical examiner believes was actually a murder.

The body of a man who stole $3 million in diamonds is found in the trunk of a car and the condition of the body makes determining the cause of death impossible.

Brenda goes toe to toe with the tricky attorney of a man suspected of a brutal rape and murder.

Fritz's sister agrees to use her psychic powers to help the Priority Homicide Division resolve one of their cases, and while her abilities appear to help her understand how Brenda works, they don't seem to stop her from offering misguided advice.

Brenda and Fritz's attention is diverted by problems on the job even though their wedding day has finally arrived, and bad blood between the members of the Priority Homicide Division threatens to cause one of the officers to leave the department.